Highly chemoselective reduction of amides (primary, secondary, tertiary) to alcohols using SmI2/amine/H2O under mild conditions.
about
Evans Enolates: Solution Structures of Lithiated Oxazolidinone-Derived Enolates.Chemoselective reduction of carboxamides.Proton-coupled electron transfer in the reduction of carbonyls using SmI2-H2O: implications for the reductive coupling of acyl-type ketyl radicals with SmI2-H2O.Deciphering a 20-Year-Old Conundrum: The Mechanisms of Reduction by the Water/Amine/SmI2 Mixture.On the role of pre- and post-electron-transfer steps in the SmI2 /amine/H(2)O-mediated reduction of esters: new mechanistic insights and kinetic studies.Evolution of a short route to strychnine by using the samarium-diiodide-induced cascade cyclization as a key step.Catalytic, asymmetric difluorination of alkenes to generate difluoromethylated stereocentersEvans Enolates: Structures and Mechanisms Underlying the Aldol Addition of Oxazolidinone-Derived Boron Enolates.Mechanistic investigation of the selective reduction of Meldrum's acids to β-hydroxy acids using SmI2 and H2O.Highly Chemoselective Synthesis of Indolizidine Lactams by SmI2 -Induced Umpolung of the Amide Bond via Aminoketyl Radicals: Efficient Entry to Alkaloid Scaffolds.Aza versus Oxophilicity of SmI2 : A Break of a Paradigm.Synthesis of Nitrogen Heterocycles Using Samarium(II) Iodide.Palladium-catalyzed Suzuki-Miyaura coupling of amides by carbon-nitrogen cleavage: general strategy for amide N-C bond activation.Direct reductive coupling of secondary amides: chemoselective formation of vicinal diamines and vicinal amino alcohols.
P2860
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P2860
Highly chemoselective reduction of amides (primary, secondary, tertiary) to alcohols using SmI2/amine/H2O under mild conditions.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
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2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
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2014年學術文章
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name
Highly chemoselective reductio ...... ine/H2O under mild conditions.
@en
type
label
Highly chemoselective reductio ...... ine/H2O under mild conditions.
@en
prefLabel
Highly chemoselective reductio ...... ine/H2O under mild conditions.
@en
P2093
P2860
P356
P1476
Highly chemoselective reductio ...... ine/H2O under mild conditions.
@en
P2093
Andrew J Eberhart
David J Procter
Malcolm Spain
Michal Szostak
P2860
P304
P356
10.1021/JA412578T
P407
P577
2014-01-31T00:00:00Z