Regulated necrosis: disease relevance and therapeutic opportunities.
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Metallothionein-1G facilitates sorafenib resistance through inhibition of ferroptosisA Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of FerroptosisNoncanocial cell death program independent of caspase activation cascade and necroptotic modules is elicited by loss of TGFβ-activated kinase 1.Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cellsTargeting iron metabolism in drug discovery and deliveryAutophagy and its link to type II diabetes mellitusApplying Precision Medicine and Immunotherapy Advances from Oncology to Host-Directed Therapies for Infectious DiseasesImmune-Mediated Nephropathy and Systemic Autoimmunity in Mice Does Not Require Receptor Interacting Protein Kinase 3 (RIPK3).Using a biologically annotated library to analyze the anticancer mechanism of serine palmitoyl transferase (SPT) inhibitors.Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degenerationA novel ligand of calcitonin receptor reveals a potential new sensor that modulates programmed cell death.Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse.PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells.Olaparib significantly delays photoreceptor loss in a model for hereditary retinal degenerationNrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis."Only a life lived for others is worth living:" Redox Signaling by Oxygenated Phospholipids in Cell Fate Decisions.Modulation of Glutathione Hemostasis by Inhibition of 12/15-Lipoxygenase Prevents ROS-Mediated Cell Death after Hepatic Ischemia and Reperfusion.ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.Keto acid metabolites of branched-chain amino acids inhibit oxidative stress-induced necrosis and attenuate myocardial ischemia-reperfusion injury.ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner.Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure.Necroptosis: A Novel Cell Death Modality and Its Potential Relevance for Critical Care Medicine.Immunopathogenesis of pancreatitis.Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion.Ischemia/Reperfusion.Iron and ferroptosis: A still ill-defined liaison.Understanding cell cycle and cell death regulation provides novel weapons against human diseases.Pharmacological modulation of cell death in organ transplantation.Susceptibility of M. tuberculosis-infected host cells to phospho-MLKL driven necroptosis is dependent on cell type and presence of TNFα.Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis.Necroptosis: Mechanisms and Relevance to Disease.The Linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis.MicroRNA-223-5p and -3p Cooperatively Suppress Necroptosis in Ischemic/Reperfused Hearts.ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage.PPAR-γ Activation Prevents Septic Cardiac Dysfunction via Inhibition of Apoptosis and NecroptosisOn the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death.6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury.PARP-1 and p53 Regulate the Increased Susceptibility to Oxidative Death of Lymphocytes from MCI and AD PatientsLipoxygenase-mediated generation of lipid peroxides enhances ferroptosis induced by erastin and RSL3.Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.
P2860
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P2860
Regulated necrosis: disease relevance and therapeutic opportunities.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Regulated necrosis: disease relevance and therapeutic opportunities.
@en
type
label
Regulated necrosis: disease relevance and therapeutic opportunities.
@en
prefLabel
Regulated necrosis: disease relevance and therapeutic opportunities.
@en
P50
P356
P1476
Regulated necrosis: disease relevance and therapeutic opportunities.
@en
P2093
Brent R Stockwell
P2888
P304
P356
10.1038/NRD.2015.6
P577
2016-01-18T00:00:00Z