Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice.
about
CRISPR-Cas9: from Genome Editing to Cancer ResearchGenetically engineered mouse models in oncology research and cancer medicineCRISPR/Cas9: Transcending the Reality of Genome Editing.Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.Targeted Genome Editing via CRISPR in the Pathogen Cryptococcus neoformans.Tissue-specific tumorigenesis: context matters.Optimization of genome editing through CRISPR-Cas9 engineeringAn easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targetingOf mice and CRISPR: The post-CRISPR future of the mouse as a model system for the human condition.Age and cellular context influence rectal prolapse formation in mice with caecal wall colorectal cancer xenografts.Chronic Pancreatitis in the 21st Century - Research Challenges and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.CRISPR-Cas9 technology: applications and human disease modelling.Applications of the CRISPR/Cas9 system in murine cancer modeling.In vivo and in vitro disease modeling with CRISPR/Cas9.Somatic Engineering of Oncogenic Chromosomal Rearrangements: A PerspectiveMicro-/nanoscale electroporation.The CRISPR/Cas9 system: Their delivery, in vivo and ex vivo applications and clinical development by startups.Somatic Genome Editing Goes Viral.Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.Site-specific chromosomal gene insertion: Flp recombinase versus Cas9 nuclease.Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity.The Future of Multiplexed Eukaryotic Genome Engineering.Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.Preclinical mouse solid tumour models: status quo, challenges and perspectives.In vivo genome editing thrives with diversified CRISPR technologies.Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities.Role of Gene Therapy in Pancreatic Cancer-A Review.CRISPR/Cas9: the Jedi against the dark empire of diseases.Activation of Rho Family GTPases by Small Molecules.Mouse models in the era of large human tumour sequencing studiesCancer modeling by Transgene Electroporation in Adult Zebrafish (TEAZ)
P2860
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P2860
Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Multiplexed pancreatic genome ...... CRISPR/Cas9 delivery in mice.
@en
type
label
Multiplexed pancreatic genome ...... CRISPR/Cas9 delivery in mice.
@en
prefLabel
Multiplexed pancreatic genome ...... CRISPR/Cas9 delivery in mice.
@en
P2093
P2860
P50
P356
P1476
Multiplexed pancreatic genome ...... CRISPR/Cas9 delivery in mice.
@en
P2093
Alexander Strong
Allan Bradley
Christian Veltkamp
Dieter Saur
Fengtang Yang
Günter Schneider
Irina Heid
Julia Weber
Mathias Friedrich
Maxim Barenboim
P2860
P2888
P356
10.1038/NCOMMS10770
P407
P50
P577
2016-02-26T00:00:00Z
P5875
P6179
1010296415