SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras. - Wikidata - awgldk - TriplyDB

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.

http://www.wikidata.org/entity/Q38713471

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Integrative Analysis of Brain Region-specific Shank3 Interactomes for Understanding the Heterogeneity of Neuronal Pathophysiology Related to SHANK3 Mutations.Meeting report - Intercellular interactions in context: towards a mechanistic understanding of cells in organs.Talin - the master of integrin adhesions.Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation.PlexinA2 Forward Signaling through Rap1 GTPases Regulates Dentate Gyrus Development and Schizophrenia-like Behaviors.Abnormalities in Interactions of Rho GTPases with Scaffolding Proteins Contribute to Neurodevelopmental Disorders.TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1.Elucidating the role of plexin D1 in body fat distribution and susceptibility to metabolic disease using a zebrafish model system.Using xCELLigence RTCA Instrument to Measure Cell Adhesion.Deficits in the Proline-Rich Synapse-Associated Shank3 Protein in Multiple Neuropsychiatric Disorders.Talin gets SHANKed in the fight for integrin activation.Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells Functional Relevance of Missense Mutations Affecting the N-Terminal Part of Shank3 Found in Autistic Patients

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P2860

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.

http://www.wikidata.org/entity/Q38713471

description

2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年论文

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2017年论文

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2017年论文

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name

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.

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type

label

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.

@en

prefLabel

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.

@en

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Nature Cell Biology

P1476

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.

@en

P2093

Fatemeh Hassani Nia

http://www.w3.org/2001/XMLSchema#string

Hans-Juergen Kreienkamp

http://www.w3.org/2001/XMLSchema#string

Igor L Barsukov

http://www.w3.org/2001/XMLSchema#string

Johanna Lilja

http://www.w3.org/2001/XMLSchema#string

Malte Beifuss

http://www.w3.org/2001/XMLSchema#string

Nicola De Franceschi

http://www.w3.org/2001/XMLSchema#string

Thomas Zacharchenko

http://www.w3.org/2001/XMLSchema#string

Tobias Boeckers

http://www.w3.org/2001/XMLSchema#string

Victoria Martens

http://www.w3.org/2001/XMLSchema#string

P2860

Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant mice

Rap1 GTPase-activating protein SPA-1 negatively regulates cell adhesion

Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairments

Mammary-derived growth inhibitor (MDGI) interacts with integrin α-subunits and suppresses integrin activity and invasion

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

SHARPIN is an endogenous inhibitor of β1-integrin activation

Mechanism of the spatio-temporal regulation of Ras and Rap1.

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

The 22q13.3 Deletion Syndrome (Phelan-McDermid Syndrome)

De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia.

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P304

292-305

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scholarly article

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10.1038/NCB3487

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4

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19

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P50

Maria Georgiadou

Guillaume Jacquemet

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17055427

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2017-03-06T00:00:00Z

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1084128687

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28263956

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5386136

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