Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.

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The Enigmatic Role of GBA2 in Controlling Locomotor Function.Biochemical Characterization of the c.1780G>C Missense Mutation in Lymphoblastoid Cells from Patients with Spastic Ataxia

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P2860

Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.

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http://www.wikidata.org/entity/Q38713961

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年论文

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2017年论文

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2017年论文

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Identification of a feedback l ...... mechanisms in Gaucher disease.

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Identification of a feedback l ...... mechanisms in Gaucher disease.

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Identification of a feedback l ...... mechanisms in Gaucher disease.

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P1476

Identification of a feedback l ...... mechanisms in Gaucher disease

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P2093

Andreas Rennhack

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Anke Penno

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Ayelet Vardi

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Britta Brügger

http://www.w3.org/2001/XMLSchema#string

Christoph Thiele

http://www.w3.org/2001/XMLSchema#string

Dagmar Wachten

http://www.w3.org/2001/XMLSchema#string

Diana N Raju

http://www.w3.org/2001/XMLSchema#string

Heinz G Körschen

http://www.w3.org/2001/XMLSchema#string

Hila Zigdon

http://www.w3.org/2001/XMLSchema#string

Katharina Gutbrod

http://www.w3.org/2001/XMLSchema#string

P2860

Ablation of neuronal ceramide synthase 1 in mice decreases ganglioside levels and expression of myelin-associated glycoprotein in oligodendrocytes

Sphingosine-1-phosphate: an enigmatic signalling lipid

Glucosylceramide transfer from lysosomes--the missing link in molecular pathology of glucosylceramidase deficiency: a hypothesis based on existing data.

METABOLISM OF GLUCOCEREBROSIDES. II. EVIDENCE OF AN ENZYMATIC DEFICIENCY IN GAUCHER'S DISEASE.

Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis.

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis.

Mutation of beta-glucosidase 2 causes glycolipid storage disease and impaired male fertility

Gaucher disease types 1, 2, and 3: differential mutations of the acid beta-glucosidase active site identified with conduritol B epoxide derivatives and sphingosine.

Accumulation of glucosylceramide in the absence of the beta-glucosidase GBA2 alters cytoskeletal dynamics.

The non-lysosomal β-glucosidase GBA2 is a non-integral membrane-associated protein at the endoplasmic reticulum (ER) and Golgi.

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6177-6189

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scholarly article

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10.1074/JBC.M116.762831

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English

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292

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Anthony H. Futerman

Bernadette Breiden

Mathias J Gerl

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2017-03-03T00:00:00Z

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28258214

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5391749

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Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.

about

P2860

P2860

Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.

description

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P1433

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