High-Potency Phenylquinoxalinone Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activators.

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Harnessing Neutrophil Survival Mechanisms during Chronic Infection by Pseudomonas aeruginosa: Novel Therapeutic Targets to Dampen Inflammation in Cystic Fibrosis Recent advances in understanding and managing chronic constipation

P2860

Q33857503-945E77E5-2DF7-4BA6-9EE9-2ED087AAB5BF Q58562464-AD6BF458-1008-49AE-82BF-1C78B1FDFFB8

P2860

High-Potency Phenylquinoxalinone Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activators.

Item

http://www.wikidata.org/entity/Q38715239

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

High-Potency Phenylquinoxalino ...... e Regulator (CFTR) Activators.

@en

type

Item

label

High-Potency Phenylquinoxalino ...... e Regulator (CFTR) Activators.

@en

prefLabel

High-Potency Phenylquinoxalino ...... e Regulator (CFTR) Activators.

@en

P1476

High-Potency Phenylquinoxalino ...... ce Regulator (CFTR) Activators

@en

P2093

Alan S Verkman

http://www.w3.org/2001/XMLSchema#string

Andrew P Teuthorn

http://www.w3.org/2001/XMLSchema#string

Colton K Ku

http://www.w3.org/2001/XMLSchema#string

Jung-Ho Son

http://www.w3.org/2001/XMLSchema#string

Onur Cil

http://www.w3.org/2001/XMLSchema#string

Puay-Wah Phuan

http://www.w3.org/2001/XMLSchema#string

P2860

Chloride channels as drug targets.

Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds.

Structure-activity studies of substituted quinoxalinones as multiple-drug-resistance antagonists.

Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation.

Nanomolar-Potency Aminophenyl-1,3,5-triazine Activators of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channel for Prosecretory Therapy of Dry Eye Diseases.

Constrained bithiazoles: small molecule correctors of defective ΔF508-CFTR protein trafficking.

TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells.

Cyanoquinolines with independent corrector and potentiator activities restore ΔPhe508-cystic fibrosis transmembrane conductance regulator chloride channel function in cystic fibrosis.

Drug-induced secretory diarrhea: A role for CFTR.

Small-molecule CFTR activators increase tear secretion and prevent experimental dry eye disease

P304

2401-2410

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/ACS.JMEDCHEM.6B01759

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Jie S Zhu

Sujin Lee

Mark J Kurth

P577

2017-03-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28230981

http://www.w3.org/2001/XMLSchema#string

P921

cystic fibrosis

transmembrane protein

P932

5463557

http://www.w3.org/2001/XMLSchema#string

High-Potency Phenylquinoxalinone Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activators.

about

P2860

P2860

High-Potency Phenylquinoxalinone Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activators.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932