Synthesis and Biological Evaluation of Novel 8-Morpholinoimidazo[1,2-a]pyrazine Derivatives Bearing Phenylpyridine/Phenylpyrimidine-Carboxamides.

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Synthesis and Biological Evaluation of Novel 8-Morpholinoimidazo[1,2-a]pyrazine Derivatives Bearing Phenylpyridine/Phenylpyrimidine-Carboxamides.

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http://www.wikidata.org/entity/Q38715666

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2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

Synthesis and Biological Evalu ...... Phenylpyrimidine-Carboxamides.

@en

type

Item

label

Synthesis and Biological Evalu ...... Phenylpyrimidine-Carboxamides.

@en

prefLabel

Synthesis and Biological Evalu ...... Phenylpyrimidine-Carboxamides.

@en

P1476

Synthesis and Biological Evalu ...... Phenylpyrimidine-Carboxamides.

@en

P2093

Chen Chen

http://www.w3.org/2001/XMLSchema#string

Chengyu Sun

http://www.w3.org/2001/XMLSchema#string

Hongying Zhou

http://www.w3.org/2001/XMLSchema#string

Pengwu Zheng

http://www.w3.org/2001/XMLSchema#string

Shan Xu

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Wufu Zhu

http://www.w3.org/2001/XMLSchema#string

Yong Zhou

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P2860

The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer

Synthesis and biological evaluation of pyrido[3',2':4,5]furo[3,2-d]pyrimidine derivatives as novel PI3 kinase p110alpha inhibitors.

PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations.

The translational landscape of mTOR signalling steers cancer initiation and metastasis

Development of PI3K inhibitors: lessons learned from early clinical trials.

Synthesis and anticancer activity of novel 4-morpholino-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine derivatives bearing chromone moiety.

Design, synthesis, biological evaluation and docking studies of novel 2-substituted-4-morpholino-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine derivatives as dual PI3Kα/mTOR inhibitors.

Synthesis, and docking studies of phenylpyrimidine-carboxamide derivatives bearing 1H-pyrrolo[2,3-b]pyridine moiety as c-Met inhibitors.

Design, synthesis, anticancer activity and docking studies of novel 4-morpholino-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine derivatives as mTOR inhibitors.

Rapid identification of ETP-46992, orally bioavailable PI3K inhibitor, selective versus mTOR.

P31

scholarly article

P356

10.3390/MOLECULES22020310

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2017-02-17T00:00:00Z

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P698

28218676

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P932

6155691

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