Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance.
about
Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity.EMT and MET: necessary or permissive for metastasis?Androgen Receptor-Dependent and -Independent Mechanisms Involved in Prostate Cancer Therapy Resistance.Impact of therapy on genomics and transcriptomics in high-risk prostate cancer treated with neoadjuvant docetaxel and androgen deprivation therapy.The dark side of SOX2: cancer - a comprehensive overview.Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-Resistant Prostate Cancer.Androgen receptor and miR-206 regulation in prostate cancer.Emerging Variants of Castration-Resistant Prostate Cancer.The intersection of RB tumor suppressor function, stem cells, metabolism and inflammation.Epithelial-to-mesenchymal transition and its role in EGFR-mutant lung adenocarcinoma and idiopathic pulmonary fibrosis.Establishment of a neuroendocrine prostate cancer model driven by the RNA splicing factor SRRM4.PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes.Beyond the androgen receptor II: New approaches to understanding and treating metastatic prostate cancer; Report from the 2017 Coffey-Holden Prostate Cancer Academy Meeting.Differential impact of RB status on E2F1 reprogramming in human cancer.Unravelling biology and shifting paradigms in cancer with single-cell sequencing.TOP2A and EZH2 Provide Early Detection of an Aggressive Prostate Cancer Subgroup.Molecular determinants of prostate cancer metastasis.Implications of PI3K/AKT inhibition on REST protein stability and neuroendocrine phenotype acquisition in prostate cancer cells.Cancer cell reprogramming to identify the genes competent for generating liver cancer stem cells.Gene expression signatures of neuroendocrine prostate cancer and primary small cell prostatic carcinoma.p53 status in the primary tumor predicts efficacy of subsequent abiraterone and enzalutamide in castration-resistant prostate cancer.Are there multiple cells of origin of Merkel cell carcinoma?Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling.Prostate Cancer Cells Express More Androgen Receptor (AR) Following Androgen Deprivation, Improving Recognition by AR-Specific T Cells.BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1.Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation.The Genomics of Prostate Cancer: emerging understanding with technologic advances.Biology and evolution of poorly differentiated neuroendocrine tumors.Current treatment strategies for advanced prostate cancer.Leveraging and coping with uncertainty in the response of individual cells to therapy.Small Cell Neuroendocrine Tumors: Cell State Trumps the Oncogenic Driver.Differential regulation of the androgen receptor by protein phosphatase regulatory subunits.Identification of potential therapeutic targets in prostate cancer through a cross-species approach.New Opportunities and Challenges to Defeat Cancer Stem Cells.SOX9 is a driver of aggressive prostate cancer by promoting invasion, cell fate and cytoskeleton alterations and epithelial to mesenchymal transition.Evasion of targeted cancer therapy through stem-cell-like reprogramming.Analytic, Preanalytic, and Clinical Validation of p53 IHC for Detection of TP53 Missense Mutation in Prostate Cancer.Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer.The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer.Gastroenteropancreatic neuroendocrine neoplasms: genes, therapies and models.
P2860
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P2860
Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Rb1 and Trp53 cooperate to sup ...... , and antiandrogen resistance.
@en
type
label
Rb1 and Trp53 cooperate to sup ...... , and antiandrogen resistance.
@en
prefLabel
Rb1 and Trp53 cooperate to sup ...... , and antiandrogen resistance.
@en
P2093
P2860
P356
P1433
P1476
Rb1 and Trp53 cooperate to sup ...... , and antiandrogen resistance.
@en
P2093
Charles L Sawyers
David W Goodrich
Eduardo Cortes Gomez
Henry W Long
Jianmin Wang
Leigh Ellis
Massimo Loda
Maxwell M Goodrich
Mukund Seshadri
P2860
P356
10.1126/SCIENCE.AAH4199
P407
P577
2017-01-01T00:00:00Z