Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells. - Wikidata - awgldk - TriplyDB

Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells.

Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells.

http://www.wikidata.org/entity/Q38736251

about

NANOG Expression as a Responsive Biomarker during Treatment with Hedgehog Signal Inhibitor in Acute Myeloid Leukemia.Phase I study of glasdegib (PF-04449913), an oral smoothened inhibitor, in Japanese patients with select hematologic malignancies.Knockdown of miR-128a induces Lin28a expression and reverts myeloid differentiation blockage in acute myeloid leukemia.Approaches for targeting self-renewal pathways in cancer stem cells: implications for hematological treatments.Development of anticancer agents targeting the Hedgehog signaling.Leukemic stem cells: identification and clinical application.Pharmacotherapeutic Targeting of G Protein-Coupled Receptors in Oncology: Examples of Approved Therapies and Emerging Concepts.Rational for targeting the hedgehog signalling pathway in acute myeloid leukemia with FLT3 mutation Advances in targeted therapy for acute myeloid leukaemia.Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy

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P2860

Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells.

http://www.wikidata.org/entity/Q38736251

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Small-molecule Hedgehog inhibi ...... acute myeloid leukemia cells.

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type

label

Small-molecule Hedgehog inhibi ...... acute myeloid leukemia cells.

@en

prefLabel

Small-molecule Hedgehog inhibi ...... acute myeloid leukemia cells.

@en

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Small-molecule Hedgehog inhibi ...... acute myeloid leukemia cells.

@en

P2093

Catoriona Jamieson

http://www.w3.org/2001/XMLSchema#string

Fumihiko Hayakawa

http://www.w3.org/2001/XMLSchema#string

Hitoshi Kiyoi

http://www.w3.org/2001/XMLSchema#string

Nobuaki Fukushima

http://www.w3.org/2001/XMLSchema#string

Seiji Kakiuchi

http://www.w3.org/2001/XMLSchema#string

Tomoki Naoe

http://www.w3.org/2001/XMLSchema#string

Yachiyo Kuwatsuka

http://www.w3.org/2001/XMLSchema#string

Yosuke Minami

http://www.w3.org/2001/XMLSchema#string

P2860

The sialomucin CD164 (MGC-24v) is an adhesive glycoprotein expressed by human hematopoietic progenitors and bone marrow stromal cells that serves as a potent negative regulator of hematopoiesis

Molecular pathways: novel approaches for improved therapeutic targeting of Hedgehog signaling in cancer stem cells

NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53.

The controversial role of the Hedgehog pathway in normal and malignant hematopoiesis.

Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration

Right on target: eradicating leukemic stem cells.

The mTOR inhibitor, everolimus (RAD001), overcomes resistance to imatinib in quiescent Ph-positive acute lymphoblastic leukemia cells.

Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma.

BCR-ABL-transformed GMP as myeloid leukemic stem cells.

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1422-1429

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scholarly article

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10.1111/CAS.13019

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10

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107

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2016-07-27T00:00:00Z

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27461445

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5084664

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