TOR complex 2-Ypk1 signaling maintains sphingolipid homeostasis by sensing and regulating ROS accumulation
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Programmed Cell Death Initiation and Execution in Budding YeastLoss of Ypk1, the yeast homolog to the human serum- and glucocorticoid-induced protein kinase, accelerates phospholipase B1-mediated phosphatidylcholine deacylationSphingolipid biosynthesis upregulation by TOR complex 2-Ypk1 signaling during yeast adaptive response to acetic acid stressTOR complex 2-Ypk1 signaling is an essential positive regulator of the general amino acid control response and autophagy.Nutrient Sensing via mTOR in T Cells Maintains a Tolerogenic Microenvironment.TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids.TOR complex 2-Ypk1 signaling regulates actin polarization via reactive oxygen species.Regulation of ceramide synthase by casein kinase 2-dependent phosphorylation in Saccharomyces cerevisiaemTORC2 is required for rit-mediated oxidative stress resistance.Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways.Functions of Ceramide Synthase Paralogs YPR114w and YJR116w of Saccharomyces cerevisiae.Characterization of AnNce102 and its role in eisosome stability and sphingolipid biosynthesis.Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated.A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial DysfunctionAmino acids trigger down-regulation of superoxide via TORC pathway in the midgut of Rhodnius prolixusCalcium channel regulator Mid1 links TORC2-mediated changes in mitochondrial respiration to autophagy.Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling.A Legume TOR Protein Kinase Regulates Rhizobium Symbiosis and Is Essential for Infection and Nodule Development.The TORC2-Dependent Signaling Network in the Yeast Saccharomyces cerevisiae.Analysis of cell cycle parameters during the transition from unhindered growth to ribosomal and translational stress conditions.Stress-response transcription factors Msn2 and Msn4 couple TORC2-Ypk1 signaling and mitochondrial respiration to ATG8 gene expression and autophagy.Protective role of the HOG pathway against the growth defect caused by impaired biosynthesis of complex sphingolipids in yeast Saccharomyces cerevisiae.Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis.TORC2 and eisosomes are spatially interdependent, requiring optimal level of phosphatidylinositol 4, 5-bisphosphate for their integrity.mTORC Inhibitors as Broad-Spectrum Therapeutics for Age-Related Diseases
P2860
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P2860
TOR complex 2-Ypk1 signaling maintains sphingolipid homeostasis by sensing and regulating ROS accumulation
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
TOR complex 2-Ypk1 signaling m ...... nd regulating ROS accumulation
@en
type
label
TOR complex 2-Ypk1 signaling m ...... nd regulating ROS accumulation
@en
prefLabel
TOR complex 2-Ypk1 signaling m ...... nd regulating ROS accumulation
@en
P2093
P2860
P1433
P1476
TOR complex 2-Ypk1 signaling m ...... nd regulating ROS accumulation
@en
P2093
Amelia C Joslin
Brad J Niles
Tara Fresques
Ted Powers
P2860
P304
P356
10.1016/J.CELREP.2013.12.040
P577
2014-01-23T00:00:00Z