Dual and Specific Inhibition of NAMPT and PAK4 By KPT-9274 Decreases Kidney Cancer Growth.
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Role of NAD+ and mitochondrial sirtuins in cardiac and renal diseasesA novel orally bioavailable compound KPT-9274 inhibits PAK4, and blocks triple negative breast cancer tumor growth.Inhibitor of Nicotinamide Phosphoribosyltransferase Sensitizes Glioblastoma Cells to Temozolomide via Activating ROS/JNK Signaling Pathway.Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma.Anticystogenic activity of a small molecule PAK4 inhibitor may be a novel treatment for autosomal dominant polycystic kidney disease.Rho GTPase effectors and NAD metabolism in cancer immune suppression.Glutamine Addiction in Kidney Cancer Suppresses Oxidative Stress and Can Be Exploited for Real-Time Imaging.Targeting the vulnerability to NAD+ depletion in B-cell acute lymphoblastic leukemia.Restoration of type 1 iodothyronine deiodinase expression in renal cancer cells downregulates oncoproteins and affects key metabolic pathways as well as anti-oxidative system.Targeting Rho GTPase effector p21 activated kinase 4 (PAK4) suppresses p-Bad-microRNA drug resistance axis leading to inhibition of pancreatic ductal adenocarcinoma proliferation.Metabolomics and Metabolic Reprogramming in Kidney Cancer.MiR-199a-3p decreases esophageal cancer cell proliferation by targeting p21 activated kinase 4.Translating Metabolic Reprogramming into New Targets for Kidney Cancer
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P2860
Dual and Specific Inhibition of NAMPT and PAK4 By KPT-9274 Decreases Kidney Cancer Growth.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Dual and Specific Inhibition o ...... ecreases Kidney Cancer Growth.
@en
type
label
Dual and Specific Inhibition o ...... ecreases Kidney Cancer Growth.
@en
prefLabel
Dual and Specific Inhibition o ...... ecreases Kidney Cancer Growth.
@en
P2093
P2860
P1476
Dual and Specific Inhibition o ...... ecreases Kidney Cancer Growth.
@en
P2093
Ching-Hsien Chen
Christian Argueta
Erkan Baloglu
Omran Abu Aboud
Robert H Weiss
William Senapedis
P2860
P304
P356
10.1158/1535-7163.MCT-16-0197
P577
2016-07-07T00:00:00Z