Calpain Genetic Disruption and HSP90 Inhibition Combine To Attenuate Mammary Tumorigenesis.

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Calpain research for drug discovery: challenges and potential.Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib

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Calpain Genetic Disruption and HSP90 Inhibition Combine To Attenuate Mammary Tumorigenesis.

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http://www.wikidata.org/entity/Q38769105

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2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Calpain Genetic Disruption and ...... tenuate Mammary Tumorigenesis.

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type

Item

label

Calpain Genetic Disruption and ...... tenuate Mammary Tumorigenesis.

@en

prefLabel

Calpain Genetic Disruption and ...... tenuate Mammary Tumorigenesis.

@en

P1476

Calpain Genetic Disruption and ...... ttenuate Mammary Tumorigenesis

@en

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Christine Hall

http://www.w3.org/2001/XMLSchema#string

Jing Hu

http://www.w3.org/2001/XMLSchema#string

Peter A Greer

http://www.w3.org/2001/XMLSchema#string

Yan Gao

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Impairment of NF-kB activation and modulation of gene expression by calpastatin

The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo

The calpain system

Targeting the dynamic HSP90 complex in cancer

Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division

Targeting multidrug resistance in cancer

Proteolysis of cortactin by calpain regulates membrane protrusion during cell migration.

Phase I study of 17-allylamino-17 demethoxygeldanamycin, gemcitabine and/or cisplatin in patients with refractory solid tumors

The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain.

Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling.

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2078-2088

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scholarly article

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10.1128/MCB.01062-15

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English

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Stacy Grieve

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2016-07-14T00:00:00Z

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27215381

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P932

4946432

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Calpain Genetic Disruption and HSP90 Inhibition Combine To Attenuate Mammary Tumorigenesis.

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P2860

P2860

Calpain Genetic Disruption and HSP90 Inhibition Combine To Attenuate Mammary Tumorigenesis.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932