Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity.
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Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy.G>C SNP of thymidylate synthase with respect to colorectal cancer.Pathway based analysis of SNPs with relevance to 5-FU therapy: relation to intratumoral mRNA expression and survival.Association of MTHFR gene polymorphisms with breast cancer survival.Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and FOLFOX response in colorectal cancer patients.Data-driven assessment of the association of polymorphisms in 5-Fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer.Polymorphisms in folate-metabolizing enzymes and response to 5-fluorouracil among patients with stage II or III rectal cancer (INT-0144; SWOG 9304).Role of the MTHFR polymorphisms in cancer risk modification and treatment.Delimiting Allelic Imbalance of TYMS by Allele-Specific AnalysisPharmacogenomics and stomach cancer.Uridine diphosphoglucuronosyl transferase and methylenetetrahydrofolate reductase polymorphisms as genomic predictors of toxicity and response to irinotecan-, antifolate- and fluoropyrimidine-based chemotherapy.Multifactorial pharmacogenetic analysis in colorectal cancer patients receiving 5-fluorouracil-based therapy together with cetuximab-irinotecan.Folic Acid-Metabolizing Enzymes Regulate the Antitumor Effect of 5-Fluoro-2'-Deoxyuridine in Colorectal Cancer Cell Lines.Genetic factors influencing pyrimidine-antagonist chemotherapy.Pharmacogenetics of colorectal cancer.Association of MTHFR C677T and A1298C gene polymorphisms with hypertensionNon-covalent interactions involving halogenated derivatives of capecitabine and thymidylate synthase: a computational approach.Hypermethylation of the DPYD promoter region is not a major predictor of severe toxicity in 5-fluorouracil based chemotherapy.Targeting One Carbon Metabolism with an Antimetabolite Disrupts Pyrimidine Homeostasis and Induces Nucleotide Overflow.Methylenetetrahydrofolate reductase (MTHFR) variants and fluorouracil-based treatments in colorectal cancer.Pharmacogenetic relevance of MTHFR polymorphisms.A retrospective comparative exploratory study on two methylentetrahydrofolate reductase (MTHFR) polymorphisms in esophagogastric cancer: the A1298C MTHFR polymorphism is an independent prognostic factor only in neoadjuvantly treated gastric cancer p5-Fluorouracil pharmacogenomics: still rocking after all these years?Recent studies of 5-fluorouracil resistance in pancreatic cancer5-Fluorouracil-based chemotherapy for colorectal cancer and MTHFR/MTRR genotypes.Pharmacogenetic analysis in neoadjuvant chemoradiation for rectal cancer: high incidence of somatic mutations and their relation with response.MTHFR gene polymorphisms and response to chemotherapy in colorectal cancer: a meta-analysis.Associations of polymorphisms of folate cycle enzymes and risk of breast cancer in a Brazilian population are age dependent.Polymorphisms in folate-related genes: impact on risk of adult acute lymphoblastic leukemia rather than pediatric in Han Chinese.DPYD*2A and MTHFR C677T predict toxicity and efficacy, respectively, in patients on chemotherapy with 5-fluorouracil for colorectal cancer.Pathway analysis of genetic variants in folate-mediated one-carbon metabolism-related genes and survival in a prospectively followed cohort of colorectal cancer patientsUse of a comprehensive panel of biomarkers to predict response to a fluorouracil-oxaliplatin regimen in patients with metastatic colorectal cancer
P2860
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P2860
Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Thymidylate synthase and methy ...... th 5-fluorouracil sensitivity.
@en
type
label
Thymidylate synthase and methy ...... th 5-fluorouracil sensitivity.
@en
prefLabel
Thymidylate synthase and methy ...... th 5-fluorouracil sensitivity.
@en
P2093
P2860
P356
P1476
Thymidylate synthase and methy ...... th 5-fluorouracil sensitivity.
@en
P2093
J-L Fischel
J-L Formento
M-C Etienne
P Formento
S Cheradame
P2860
P2888
P304
P356
10.1038/SJ.BJC.6601523
P407
P577
2004-01-01T00:00:00Z
P5875
P6179
1007639539