Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis.
about
Autophagy is involved in aldosterone‑induced mesangial cell proliferation.Accumulation of autophagosomes confers cytotoxicity.The Contribution of Necroptosis in Neurodegenerative Diseases.The interplay between autophagy and tumorigenesis: exploiting autophagy as a means of anticancer therapy.Impaired lysosomal activity mediated autophagic flux disruption by graphite carbon nanofibers induce apoptosis in human lung epithelial cells through oxidative stress and energetic impairmentEscherichia coli O157:H7 suppresses host autophagy and promotes epithelial adhesion via Tir-mediated and cAMP-independent activation of protein kinase ASmall molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells.High mobility group A1 protein modulates autophagy in cancer cells.Inhibiting MT2-TFE3-dependent autophagy enhances melatonin-induced apoptosis in tongue squamous cell carcinoma.Pan-class I PI3-kinase inhibitor BKM120 induces MEK1/2-dependent mitotic catastrophe in non-Hodgkin lymphoma leading to apoptosis or polyploidy determined by Bax/Bak and p53.Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication.
P2860
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P2860
Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Dual PI-3 kinase/mTOR inhibiti ...... of apoptosis and necroptosis.
@en
type
label
Dual PI-3 kinase/mTOR inhibiti ...... of apoptosis and necroptosis.
@en
prefLabel
Dual PI-3 kinase/mTOR inhibiti ...... of apoptosis and necroptosis.
@en
P2093
P2860
P356
P1433
P1476
Dual PI-3 kinase/mTOR inhibiti ...... of apoptosis and necroptosis.
@en
P2093
Conor J Strang
Joseph H Vincent
Robert W Button
Shouqing Luo
P2860
P304
P356
10.18632/ONCOTARGET.6986
P407
P577
2016-01-22T00:00:00Z