about
X-ray structure of Salmonella typhimurium uridine phosphorylase complexed with 5-fluorouracil and molecular modelling of the complex of 5-fluorouracil with uridine phosphorylase from Vibrio choleraeDisordering of human telomeric G-quadruplex with novel antiproliferative anthrathiophenedioneDissecting eukaryotic cells by coherent phase microscopy: quantitative analysis of quiescent and activated T lymphocytes.Boronated protohaemins: synthesis and in vivo antitumour efficacy.Bacterial eukaryotic type serine-threonine protein kinases: from structural biology to targeted anti-infective drug design.Expression of genes of glutathione transferase isoforms GSTP1-1, GSTA4-4, and GSTK1-1 in tumor cells during the formation of drug resistance to cisplatin.Emergence of multidrug resistance in leukemia cells during chemotherapy: mechanisms and prevention.Novel Indolocarbazole Derivative 12-(α-L-arabinopyranosyl)indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione Is a Preferred c-Myc Guanine Quadruplex Ligand.Virtual screening of chemical compounds active against breast cancer cell lines based on cell cycle modelling, prediction of cytotoxicity and interaction with targets.Redundancy of biological regulation as the basis of emergence of multidrug resistance.Ether lipids as anticancer agents: focus on non-phosphorus cationic glycerolipids.In silico design of protein kinase inhibitors: successes and failures.The water channels, new druggable targets to combat cancer cell survival, invasiveness and metastasis.N-benzoxazol-2-yl-N'-1-(isoquinolin-3-yl-ethylidene)-hydrazine, a novel compound with antitumor activity, induces radicals and dissipation of mitochondrial membrane potential.The role of carboxymethyl substituents in the interaction of tetracationic porphyrins with DNA.Conjugates of phosphorylated zalcitabine and lamivudine with SiO2 nanoparticles: Synthesis by CuAAC click chemistry and preliminary assessment of anti-HIV and antiproliferative activity.Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties.Synthesis and Characterization of 4,11-Diaminoanthra[2,3-b]furan-5,10-diones: Tumor Cell Apoptosis through tNOX-Modulated NAD(+)/NADH Ratio and SIRT1.Developing Antitumor Magnetic Hyperthermia: Principles, Materials and Devices.Novel multi-targeting anthra[2,3-b]thiophene-5,10-diones with guanidine-containing side chains: interaction with telomeric G-quadruplex, inhibition of telomerase and topoisomerase I and cytotoxic properties.Novel fluorescent pyrimidine nucleosides containing 2,1,3-benzoxadiazole and naphtho-[1,2,3-CD] Indole-6 (2H)-one fragments.Study on retroaldol degradation products of antibiotic oligomycin A.Quantitative phase imaging of living cells: application of the phase volume and area functions to the analysis of "nucleolar stress".Role of the acyl groups in carbohydrate chains in cytotoxic properties of olivomycin A.Synthesis and cytotoxicity of oligomycin A derivatives modified in the side chain.Modification of olivomycin A at the side chain of the aglycon yields the derivative with perspective antitumor characteristics.The first series of 4,11-bis[(2-aminoethyl)amino]anthra[2,3-b]furan-5,10-diones: Synthesis and anti-proliferative characteristics.Synthesis and cytotoxic potency of novel tris(1-alkylindol-3-yl)methylium salts: role of N-alkyl substituents.Novel antitumor L-arabinose derivative of indolocarbazole with high affinity to DNA.Reaction of the antitumor antibiotic olivomycin I with aryl diazonium salts. Synthesis, cytotoxic and antiretroviral potency of 5-aryldiazenyl-6-O-deglycosyl derivatives of olivomycin I.Synthesis and cytotoxic properties of 4,11-bis[(aminoethyl)amino]anthra[2,3-b]thiophene-5,10-diones, novel analogues of antitumor anthracene-9,10-diones.Modification of the antibiotic olivomycin I at the 2'-keto group of the side chain. Novel derivatives, antitumor and topoisomerase I-poisoning activity.Quantitative real-time analysis of nucleolar stress by coherent phase microscopy.Novel boronated chlorin e6-based photosensitizers: synthesis, binding to albumin and antitumour efficacy.Naphthoindole-based analogues of tryptophan and tryptamine: synthesis and cytotoxic properties.Synthesis and structure-activity relationship studies of 4,11-diaminonaphtho[2,3-f]indole-5,10-diones.Novel boronated derivatives of 5,10,15,20-tetraphenylporphyrin: synthesis and toxicity for drug-resistant tumor cells.Olivomycin induces tumor cell apoptosis and suppresses p53-induced transcription.3-Aminomethyl derivatives of 4,11-dihydroxynaphtho[2,3-f]indole-5,10-dione for circumvention of anticancer drug resistance.Role of phosphatidylinositol-3 kinase in regulation of differential sensitivity of melanoma cells to antitumor agents. A model for hormone resistance development in tumor cells.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Alexander A. Shtil
@ast
Alexander A. Shtil
@en
Alexander A. Shtil
@es
Alexander A. Shtil
@nl
Alexander Albertowitsch Schtil
@de
Александр Альбертович Штиль
@ru
type
label
Alexander A. Shtil
@ast
Alexander A. Shtil
@en
Alexander A. Shtil
@es
Alexander A. Shtil
@nl
Alexander Albertowitsch Schtil
@de
Александр Альбертович Штиль
@ru
altLabel
Aleksandr Albertovich Shtil
@en
Aleksandr Shtil
@en
Alexander Schtil
@de
Alexander Shtil
@en
prefLabel
Alexander A. Shtil
@ast
Alexander A. Shtil
@en
Alexander A. Shtil
@es
Alexander A. Shtil
@nl
Alexander Albertowitsch Schtil
@de
Александр Альбертович Штиль
@ru
P1053
K-1568-2017
P106
P1153
6701822067
P21
P31
P3829
P496
0000-0001-6469-0221