Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1-Transfected Human Embryonic Kidney 293 Cells.
about
Molecular features of biguanides required for targeting of mitochondrial respiratory complex I and activation of AMP-kinase.Intracellular drug bioavailability: a new predictor of system dependent drug disposition.A Structural Basis for Biguanide Activity.Polyspecific organic cation transporters and their impact on drug intracellular levels and pharmacodynamics.Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery.Intracellular Unbound Atorvastatin Concentrations in the Presence of Metabolism and Transport.Mechanisms for restraining cAMP-dependent protein kinase revealed by subunit quantitation and cross-linking approaches.Genetic Heterogeneity of SLC22 Family of Transporters in Drug Disposition.Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy.Biguanides enhance antifungal activity against Candida glabrataMetformin: An Old Drug with New Applications
P2860
Q36099352-8677A43A-7081-4CC8-B193-24AF1015C782Q36287236-B33879F4-0F4E-4912-A19D-3958AE1ED9FAQ38647178-F700D2F3-5C57-40BF-9EAB-0AEE064EA11BQ38851414-D0D9C790-5B21-488D-B1E0-1C6A98D8F0A8Q41256404-7307BE46-2381-46A5-BDE8-0F88195B034AQ41651472-7F2B300B-9723-447A-AA46-E66050CAC2DEQ47820498-303EF9E9-4D73-4403-A374-1B3FF58257B7Q55514622-A8D7EF3C-94F9-4378-BAA6-475D46A81C6FQ55516148-75FB04A3-4426-408F-AD12-767FEB43C697Q58806129-4276DD86-F768-4BE5-9BAC-E59C78770EBBQ59138339-ACC2DE5F-1BD0-4814-A2CB-7D8DC7305BBE
P2860
Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1-Transfected Human Embryonic Kidney 293 Cells.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Rapid Method To Determine Intr ...... an Embryonic Kidney 293 Cells.
@en
type
label
Rapid Method To Determine Intr ...... an Embryonic Kidney 293 Cells.
@en
prefLabel
Rapid Method To Determine Intr ...... an Embryonic Kidney 293 Cells.
@en
P2093
P2860
P356
P1476
Rapid Method To Determine Intr ...... man Embryonic Kidney 293 Cells
@en
P2093
Arik A Zur
Huan-Chieh Chien
John Tolsma
Kathleen M Giacomini
Paul Jasper
Tristan S Maurer
P2860
P304
P356
10.1124/DMD.115.066647
P577
2015-12-23T00:00:00Z