Perspective: 4β-hydroxycholesterol as an emerging endogenous biomarker of hepatic CYP3A.

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Strategy for CYP3A Induction Risk Assessment from Preclinical Signal to Human: a Case Example of a Late-Stage Discovery Compound.Randomized clinical study of safety, pharmacokinetics, and pharmacodynamics of RIPK1 inhibitor GSK2982772 in healthy volunteers.

P2860

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Perspective: 4β-hydroxycholesterol as an emerging endogenous biomarker of hepatic CYP3A.

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

@zh-cn

name

Perspective: 4β-hydroxycholesterol as an emerging endogenous biomarker of hepatic CYP3A.

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type

Item

label

Perspective: 4β-hydroxycholesterol as an emerging endogenous biomarker of hepatic CYP3A.

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prefLabel

Perspective: 4β-hydroxycholesterol as an emerging endogenous biomarker of hepatic CYP3A.

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P1476

Perspective: 4β-hydroxycholesterol as an emerging endogenous biomarker of hepatic CYP3A.

@en

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Gail Nolan

http://www.w3.org/2001/XMLSchema#string

Iain Martin

http://www.w3.org/2001/XMLSchema#string

James McLeod

http://www.w3.org/2001/XMLSchema#string

Jialin Mao

http://www.w3.org/2001/XMLSchema#string

Manoli Vourvahis

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Robert van Horn

http://www.w3.org/2001/XMLSchema#string

Yvonne S Lin

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Do oxysterols control cholesterol homeostasis?

Genetic contribution to variable human CYP3A-mediated metabolism

Enterocytic CYP3A4 in a paediatric population: developmental changes and the effect of coeliac disease and cystic fibrosis

Circadian variation of the urinary 6beta-hydroxycortisol to cortisol ratio that would reflect hepatic CYP3A activity.

Oxysterols and their cellular effectors.

Pharmacokinetic interactions between ritonavir and quinine in healthy volunteers following concurrent administration

Comparison of two endogenous biomarkers of CYP3A4 activity in a drug-drug interaction study between midostaurin and rifampicin.

Cytochrome p450 turnover: regulation of synthesis and degradation, methods for determining rates, and implications for the prediction of drug interactions.

Hepatic cytochrome P450 regulation in disease states.

Validation of 4β-hydroxycholesterol and evaluation of other endogenous biomarkers for the assessment of CYP3A activity in healthy subjects

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18-34

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scholarly article

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10.1080/03602532.2016.1239630

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English

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http://www.w3.org/2001/XMLSchema#string

P478

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2016-10-10T00:00:00Z

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27718639

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P921

biomarker

Perspective: 4β-hydroxycholesterol as an emerging endogenous biomarker of hepatic CYP3A.

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P2860

P2860

Perspective: 4β-hydroxycholesterol as an emerging endogenous biomarker of hepatic CYP3A.

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P1433

P1476

P2093

P2860

P304

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P356

P407

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P577

P698

P921

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P921