The peripheral antinociceptive effect induced by morphine is associated with ATP-sensitive K(+) channels
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Dibutyryl-cyclic GMP induces peripheral antinociception via activation of ATP-sensitive K(+) channels in the rat PGE2-induced hyperalgesic pawActivation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability of DRG neurons from ratsMorphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathwayPeripheral G protein-coupled inwardly rectifying potassium channels are involved in δ-opioid receptor-mediated anti-hyperalgesia in rat masseter muscle.ATP-sensitive Potassium Channels and L-type Calcium Channels are Involved in Morphine-induced Hyperalgesia after Nociceptive Sensitization in MiceCitronellal, a monoterpene present in Java citronella oil, attenuates mechanical nociception response in mice.Activation of presynaptic NMDA receptors coupled to NaV1.8-resistant sodium channel C-fibers causes retrograde mechanical nociceptor sensitization.Sex differences in the contribution of ATP-sensitive K+ channels in trigeminal ganglia under an acute muscle pain conditionAntinociceptive activity of methanolic extract of Muntingia calabura leaves: further elucidation of the possible mechanismsActivation of peripheral delta-opioid receptors leads to anti-hyperalgesic responses in the masseter muscle of male and female ratsATP-sensitive potassium currents reduce the PGE2-mediated enhancement of excitability in adult rat sensory neuronsEndogenous morphine: opening new doors for the treatment of pain and addiction.Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K+ channel pathway.Participation of the NO/cGMP/K+ATP pathway in the antinociception induced by Walker tumor bearing in ratsLocal antinociceptive action of fluoxetine in the rat formalin assay: Role of L-arginine-nitric oxide-cGMP-KATP channel pathway.Systemic and local anti-nociceptive effects of simvastatin in the rat formalin assay: Role of peroxisome proliferator-activated receptor γ and nitric oxide.Effect of transcutaneous electrical stimulation on nociception and edema induced by peripheral serotonin.Hydrogen sulphide induces micro opioid receptor-dependent analgesia in a rodent model of visceral pain.NOSH-aspirin (NBS-1120), a dual nitric oxide and hydrogen sulfide-releasing hybrid, reduces inflammatory pain.Baclofen, an agonist at peripheral GABAB receptors, induces antinociception via activation of TEA-sensitive potassium channelsNitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation.Role of pertussis toxin-sensitive G-protein, K+ channels, and voltage-gated Ca2+ channels in the antinociceptive effect of inosineOpposite nociceptive effects of the arginine/NO/cGMP pathway stimulation in dermal and subcutaneous tissues.Stimulation of peripheral kappa opioid receptors inhibits inflammatory hyperalgesia via activation of the PI3Kγ/AKT/nNOS/NO signaling pathway.Different mechanisms underlie the analgesic actions of paracetamol and dipyrone in a rat model of inflammatory pain.Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons.Discovery and development of tramadol for the treatment of pain.Clonidine-induced antinociception and locomotor hypoactivity are reduced by dexamethasone in mice.Few cultured rat primary sensory neurons express a tolbutamide-sensitive K+ current.Mu, delta, and kappa opioid receptor agonists induce peripheral antinociception by activation of endogenous noradrenergic system.δ-Opioid receptor agonist SNC80 induces central antinociception mediated by Ca2+ -activated Cl- channels.The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats.The L-arginine/nitric oxide/cyclic-GMP pathway apparently mediates the peripheral antihyperalgesic action of fentanyl in rats.Participation of ATP-sensitive K+ channels in the peripheral antinociceptive effect of fentanyl in rats.Skin vasodilation and analgesic effect of a topical nitric oxide-releasing hydrogel.Antinociceptive Activities of the Methanolic Extract of the Stem Bark of Boswellia dalzielii Hutch. (Burseraceae) in Rats Are NO/cGMP/ATP-Sensitive-K+ Channel Activation Dependent.Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain.Tingenone, a pentacyclic triterpene, induces peripheral antinociception due to cannabinoid receptors activation in mice.Oxytocin down-regulates mesenteric afferent sensitivity via the enteric OTR/nNOS/NO/KATP pathway in rat.Role of L-arginine/NO/cGMP/KATP channel signaling pathway in the central and peripheral antinociceptive effect of thymoquinone in rats.
P2860
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P2860
The peripheral antinociceptive effect induced by morphine is associated with ATP-sensitive K(+) channels
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
The peripheral antinociceptive ...... th ATP-sensitive K(+) channels
@en
type
label
The peripheral antinociceptive ...... th ATP-sensitive K(+) channels
@en
prefLabel
The peripheral antinociceptive ...... th ATP-sensitive K(+) channels
@en
P2860
P356
P1476
The peripheral antinociceptive ...... th ATP-sensitive K(+) channels
@en
P2093
A R Rodrigues
I D Duarte
P2860
P304
P356
10.1038/SJ.BJP.0703038
P407
P577
2000-01-01T00:00:00Z