Molecular Basis of Metabolism-Mediated Conversion of PK11195 from an Antagonist to an Agonist of the Constitutive Androstane Receptor.

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Molecular Basis of Metabolism-Mediated Conversion of PK11195 from an Antagonist to an Agonist of the Constitutive Androstane Receptor.

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2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

Molecular Basis of Metabolism- ...... stitutive Androstane Receptor.

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type

Item

label

Molecular Basis of Metabolism- ...... stitutive Androstane Receptor.

@en

prefLabel

Molecular Basis of Metabolism- ...... stitutive Androstane Receptor.

@en

P1476

Molecular Basis of Metabolism- ...... stitutive Androstane Receptor.

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P2093

Bryan Mackowiak

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Daochuan Li

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Hongbing Wang

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Jace W Jones

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Linhao Li

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Matthew A Welch

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Maureen A Kane

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Peter W Swaan

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Scott Heyward

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P2860

Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

Xenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

Molecular dynamics simulations of the human CAR ligand-binding domain: deciphering the molecular basis for constitutive activity.

Phenobarbital-elicited activation of nuclear receptor CAR in induction of cytochrome P450 genes.

Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation.

Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.

Differential activation of pregnane X receptor and constitutive androstane receptor by buprenorphine in primary human hepatocytes and HepG2 cells.

Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR).

Multi-species analyses of direct activators of the constitutive androstane receptor.

P304

75-87

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P31

scholarly article

P356

10.1124/MOL.117.108621

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P433

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P478

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P577

2017-04-25T00:00:00Z

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P698

28442602

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P932

5452073

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