From transcriptomic to protein level changes in TDP-43 and FUS loss-of-function cell models.
about
TDP-43 and FUS en route from the nucleus to the cytoplasm.TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins.Role of FET proteins in neurodegenerative disorders.Failure to Deliver and Translate-New Insights into RNA Dysregulation in ALS.Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells.Alternative splicing of CNOT7 diversifies CCR4-NOT functions.Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice.Reduced stress granule formation and cell death in fibroblasts with the A382T mutation of TARDBP gene: evidence for loss of TDP-43 nuclear function.Pathomechanisms of TDP-43 in neurodegeneration.TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.
P2860
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P2860
From transcriptomic to protein level changes in TDP-43 and FUS loss-of-function cell models.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
From transcriptomic to protein ...... loss-of-function cell models.
@en
type
label
From transcriptomic to protein ...... loss-of-function cell models.
@en
prefLabel
From transcriptomic to protein ...... loss-of-function cell models.
@en
P2093
P50
P1476
From transcriptomic to protein ...... S loss-of-function cell models
@en
P2093
Antonia Ratti
Elisa Onesto
Francisco E Baralle
Vincenzo Silani
P304
P356
10.1016/J.BBAGRM.2015.10.015
P407
P577
2015-10-26T00:00:00Z