PKM2 Promotes Cell Survival and Invasion Under Metabolic Stress by Enhancing Warburg Effect in Pancreatic Ductal Adenocarcinoma. - Wikidata - awgldk - TriplyDB

PKM2 Promotes Cell Survival and Invasion Under Metabolic Stress by Enhancing Warburg Effect in Pancreatic Ductal Adenocarcinoma.

PKM2 Promotes Cell Survival and Invasion Under Metabolic Stress by Enhancing Warburg Effect in Pancreatic Ductal Adenocarcinoma.

http://www.wikidata.org/entity/Q38824976

about

PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer.CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming.Induction of apoptosis by FFJ-5, a novel naphthoquinone compound, occurs via downregulation of PKM2 in A549 and HepG2 cells.Pyruvate kinase M2 (PKM2) expression correlates with prognosis in solid cancers: a meta-analysis.Linc-ROR confers gemcitabine resistance to pancreatic cancer cells via inducing autophagy and modulating the miR-124/PTBP1/PKM2 axis.Upregulation of pyruvate kinase M2 expression by fatty acid synthase contributes to gemcitabine resistance in pancreatic cancer.Pyruvate kinase M2 promotes pancreatic ductal adenocarcinoma invasion and metastasis through phosphorylation and stabilization of PAK2 protein.PKM2 is not required for pancreatic ductal adenocarcinoma

P2860

Q33767514-64DC467B-8DD4-493C-A410-89E52E33F704 Q37686894-CB09B964-83A3-4CC1-BAB0-AE734E9F5A94 Q37701047-569BD5ED-CDC2-4FBC-9613-433E37F78B9F Q37702143-F9807D98-1B95-4DF9-884C-577D067681B1 Q38736389-D07067A9-1000-467C-9C7B-ADC829F97CC4 Q49685991-15BD6D97-AA5C-424E-99C7-4396BE0D54C6 Q50042580-69FAC48F-CD3A-4C73-A233-5F67136C5FA7 Q58570870-98B2B26E-6C53-4046-92E6-4170B8084156

P2860

PKM2 Promotes Cell Survival and Invasion Under Metabolic Stress by Enhancing Warburg Effect in Pancreatic Ductal Adenocarcinoma.

http://www.wikidata.org/entity/Q38824976

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

PKM2 Promotes Cell Survival an ...... creatic Ductal Adenocarcinoma.

@en

type

label

PKM2 Promotes Cell Survival an ...... creatic Ductal Adenocarcinoma.

@en

prefLabel

PKM2 Promotes Cell Survival an ...... creatic Ductal Adenocarcinoma.

@en

P1433

Q38824976-1A1153F1-9C46-4941-9878-E5BE9A71DDB7

P1476

Q38824976-EEAFA7EF-C977-4081-9227-CB62EEBF9710

P2093

Q38824976-1AD43B5D-A3C3-4393-8468-D0EF2BA72B85

Q38824976-6D403ABF-7CED-494D-A1BA-25C48DEDB323

Q38824976-8AD2536D-2F20-4684-B5D2-399B2461EC41

Q38824976-9E92C2F5-7812-480A-AEC5-2F3D7376F312

P2860

Q38824976-1B7945BB-A2BA-4237-9DD7-86155A7C17BB

Q38824976-1CF40BCB-2044-4564-A669-6551198B9F80

Q38824976-1E0C353E-11F7-4B62-8235-CC3FB544D7ED

Q38824976-2F8CA0E4-CF14-453E-A0AA-8D5B4FB71DA2

Q38824976-51386E57-445F-497E-B9DB-F16B8E952AE2

Q38824976-53841CFC-DB30-418F-B8A7-97782CED0835

Q38824976-57F971F6-807B-493F-937B-F81004506160

Q38824976-5A494F3A-3086-4B1E-937D-DDF8164347E6

Q38824976-5BC8D15D-7BBB-4319-A5A1-BB361D8E7ADF

Q38824976-68A5CE19-554C-4316-8865-EB2A3A5E7565

P2888

Q38824976-A79F110C-3B25-4FDD-A8F9-4AF214EB5A54

P304

Q38824976-631584EC-B0BE-4DB5-A592-BDAD16C66B9C

P31

Q38824976-BC2A133D-CBEE-451E-B061-CD95EDA3728F

P356

Q38824976-D0D653D3-08E3-4E9E-AD8A-D4FF2E2DD0C6

P433

Q38824976-468C80AE-D08A-4A60-BE32-256416B8B731

P478

Q38824976-DD092C7C-94E8-4A6B-9ECF-FF63694B4DAC

P577

Q38824976-7835F668-3221-45BC-AA43-9F453F705B76

P6179

Q38824976-005DD110-00F0-49CC-8B3D-9D74FA755AF9

P698

Q38824976-DDA69957-1408-4F28-8D46-AB120B7FAE6B

P356

S10620-015-3931-2

P1433

Digestive Diseases and Sciences

P1476

PKM2 Promotes Cell Survival an ...... creatic Ductal Adenocarcinoma.

@en

P2093

Chenggang Li

http://www.w3.org/2001/XMLSchema#string

Rong Liu

http://www.w3.org/2001/XMLSchema#string

Zhiming Zhao

http://www.w3.org/2001/XMLSchema#string

Zhipeng Zhou

http://www.w3.org/2001/XMLSchema#string

P2860

Hallmarks of Cancer: The Next Generation

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Global cancer statistics, 2012

PKM2: the thread linking energy metabolism reprogramming with epigenetics in cancer

Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.

Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells

PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

PKM2 as a biomarker for chemosensitivity to front-line platinum-based chemotherapy in patients with metastatic non-small-cell lung cancer.

Pyruvate kinase M2 prevents apoptosis via modulating Bim stability and associates with poor outcome in hepatocellular carcinoma.

P2888

s10620-015-3931-2

P304

767-773

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S10620-015-3931-2

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

61

http://www.w3.org/2001/XMLSchema#string

P577

2015-10-24T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P6179

1039771467

http://www.w3.org/2001/XMLSchema#string

P698

26500118

http://www.w3.org/2001/XMLSchema#string