Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing.
about
Customizing the genome as therapy for the β-hemoglobinopathiesTargeting protein function: the expanding toolkit for conditional disruptionCancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motifHighly efficient biallelic genome editing of human ES/iPS cells using a CRISPR/Cas9 or TALEN system.CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair.Gene cassette knock-in in mammalian cells and zygotes by enhanced MMEJFunctional interrogation of non-coding DNA through CRISPR genome editing.Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cellsCo-incident insertion enables high efficiency genome engineering in mouse embryonic stem cells.CRISPR RNA-guided FokI nucleases repair a PAH variant in a phenylketonuria model.Efficient Generation of Orthologous Point Mutations in Pigs via CRISPR-assisted ssODN-mediated Homology-directed Repair.Seipin regulates ER-lipid droplet contacts and cargo delivery.Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavageCRISPR/Cas9-Mediated Genome Editing Corrects Dystrophin Mutation in Skeletal Muscle Stem Cells in a Mouse Model of Muscle Dystrophy.Developmental history and application of CRISPR in human disease.A mechanism for the suppression of homologous recombination in G1 cells.CRISPR-Cas9 technology and its application in haematological disorders.Gene correction in patient-specific iPSCs for therapy development and disease modeling.A comprehensive overview of computational resources to aid in precision genome editing with engineered nucleases.Emerging cellular and gene therapies for congenital anemias.CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.Precision genome editing in the CRISPR era.Mammalian synthetic biology in the age of genome editing and personalized medicine.Hematopoietic Stem Cell Gene Therapy: Progress and Lessons Learned.Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency.A convenient method to pre-screen candidate guide RNAs for CRISPR/Cas9 gene editing by NHEJ-mediated integration of a 'self-cleaving' GFP-expression plasmid.Disruption of diphthamide synthesis genes and resulting toxin resistance as a robust technology for quantifying and optimizing CRISPR/Cas9-mediated gene editing.CRISPR Genome Engineering for Human Pluripotent Stem Cell Research.Beyond editing to writing large genomes.Loss of PRP4K drives anoikis resistance in part by dysregulation of epidermal growth factor receptor endosomal trafficking.Marker-free coselection for CRISPR-driven genome editing in human cells.Control of gene editing by manipulation of DNA repair mechanisms.BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.Accelerated homology-directed targeted integration of transgenes in Chinese hamster ovary cells via CRISPR/Cas9 and fluorescent enrichment.Coupling of Homologous Recombination and the Checkpoint by ATR.An efficient platform for generating somatic point mutations with germline transmission in the zebrafish by CRISPR/Cas9-mediated gene editing.GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1.Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells.Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells.Efficient Knock-in of a Point Mutation in Porcine Fibroblasts Using the CRISPR/Cas9-GMNN Fusion Gene.
P2860
Q26751061-46442168-BB9D-4C47-914C-0FED132FEA93Q28074840-DDC41F32-1196-4480-8CCC-D5EDBF5237A9Q33558127-BECB4804-CC19-4DA9-BFDE-E428F5795911Q33701667-95323F74-0F72-4BE0-9651-BB0066997BEDQ33725333-2E6634F7-96DC-42D1-9F49-8D5D1CB5DCE5Q34546043-381EE328-E076-4DCE-A078-0024947ED997Q36306820-8908F54F-353C-4DBB-A3B8-72E058D12E84Q36412556-D9ADBED9-AB95-489C-84D7-4F3E592A2C15Q37264419-08164A0C-5981-4492-9AFA-CF6FA3921967Q37369090-F191ED8C-9496-4D77-B5EA-C48078B775F0Q37501565-3CA044AA-C3F0-49DA-9F78-2B2BA2F980A3Q37515456-6F35B77F-C8BC-49DE-A2B7-3848F3ED0CB1Q37655265-D962698A-DA50-4FFB-8CB0-D13486D2B409Q37718519-C2D2F40E-C874-4631-9B11-6026D56A99F0Q38669948-AFFAD4FF-EC02-45CF-82A5-9B70B40EF7B5Q38813207-DACF92EF-4F48-421E-95D8-315CA7032F43Q38822073-2717DF3F-B7FB-4DB9-8D07-AD1E72A36828Q38852141-EABD6A89-2DE0-4EC2-8318-328F52D2AB9BQ38884774-B136983A-1BA3-4BDC-AD70-0C3A2B67D2EFQ38993825-5DB746E7-08AB-4CC5-9DF3-6C14607F252CQ39014648-C5154814-EBA9-470F-AC08-2D35A5EC9167Q39126189-6BA5C5CC-C135-4086-870F-EEB021731323Q39383306-7D16620E-EF1B-4BE4-8830-9EC7837D7BA2Q45873930-5C2CB8F6-7FBD-4F0E-AD31-809010C27453Q46257646-BC18018F-65A9-4096-AD4F-9421F5FF7A2BQ46340316-4010D412-2050-4CA6-B8C0-75C39CE68251Q46440057-24EABEFF-9B9F-4F8B-BCDD-2E92DA74245CQ46522290-37EDECB6-3676-40C9-A590-970165D55B62Q47324234-DC7AA1B4-0929-48D0-A32F-DE1AA29677FAQ48095106-2304DDA0-7E02-47A4-954B-35575ED70E02Q48266764-5F5C7268-87BA-4DA4-A686-9368F3C82FC6Q48325841-7057B56E-364B-46EA-A093-6E15792CC09BQ49612029-33241B43-3C59-459B-B28C-EECCAEC4F448Q50854995-E3526920-EEFD-495F-A861-26B83649D444Q50952398-7A95DF1C-BA1F-4859-ACFB-852A7B12E6CDQ52430570-77B991B3-B9E0-4D95-A00F-360767FA803DQ52719689-51FE0F02-E597-49FE-A6E1-71EC77E4CC2AQ55069666-6D2697C0-1A61-432B-B52E-3176B7A019D4Q55168127-571E9EEE-4A14-4B18-9DCB-92235386C52FQ55687327-D3D44E99-CF09-481F-9740-E231187BE514
P2860
Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Nuclear domain 'knock-in' scre ...... f CRISPR-based genome editing.
@en
type
label
Nuclear domain 'knock-in' scre ...... f CRISPR-based genome editing.
@en
prefLabel
Nuclear domain 'knock-in' scre ...... f CRISPR-based genome editing.
@en
P2860
P356
P1476
Nuclear domain 'knock-in' scre ...... f CRISPR-based genome editing.
@en
P2093
Jayme Salsman
Jordan Pinder
P2860
P304
P356
10.1093/NAR/GKV993
P407
P577
2015-10-01T00:00:00Z