Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
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Recent insights into the molecular mechanisms of the NLRP3 inflammasome activationNanoparticle-Based and Bioengineered Probes and Sensors to Detect Physiological and Pathological Biomarkers in Neural CellsShigella IpaH Family Effectors as a Versatile Model for Studying Pathogenic BacteriaThe Roles of RNase-L in Antimicrobial Immunity and the Cytoskeleton-Associated Innate ResponseInnate Immune Response in Brain, NF-Kappa B Signaling and CystatinsConverging roles of caspases in inflammasome activation, cell death and innate immunityDangerous Liaisons: Caspase-11 and Reactive Oxygen Species Crosstalk in Pathogen EliminationInflammasome-dependent IL-1β release depends upon membrane permeabilisationIntegrating Inflammasome Signaling in Sexually Transmitted InfectionsEmerging Roles for the Immune System in Traumatic Brain InjuryThe cell biology of inflammasomes: Mechanisms of inflammasome activation and regulationGasdermin D is an executor of pyroptosis and required for interleukin-1β secretionThe intersection of cell death and inflammasome activationInflammasome-activated gasdermin D causes pyroptosis by forming membrane poresInterferon-induced guanylate-binding proteins in inflammasome activation and host defenseChemical chaperone TUDCA prevents apoptosis and improves survival during polymicrobial sepsis in miceGSDMD membrane pore formation constitutes the mechanism of pyroptotic cell deathGrowth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death.Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.Emerging roles for lipids in non-apoptotic cell deathDnase1L3 Regulates Inflammasome-Dependent Cytokine Secretion.Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases.Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or NecrosisProteases Revisited: Roles and Therapeutic Implications in Fibrosis.Foxo3a-dependent Bim transcription protects mice from a high fat diet via inhibition of activation of the NLRP3 inflammasome by facilitating autophagy flux in Kupffer cells.Programmed necrosis in inflammation: Toward identification of the effector molecules.A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome ActivationP2X7 receptor-mediated TG2 externalization: a link to inflammatory arthritis?Lymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares.Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1βCaspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance.Detection of a microbial metabolite by STING regulates inflammasome activation in response to Chlamydia trachomatis infection.AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunityQuantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles.Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in miceManipulation of Interleukin-1β and Interleukin-18 Production by Yersinia pestis Effectors YopJ and YopM and Redundant Impact on Virulence.Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation.ASC filament formation serves as a signal amplification mechanism for inflammasomes
P2860
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P2860
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
@en
type
label
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
@en
prefLabel
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
@en
P2093
P50
P356
P1433
P1476
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
@en
P2093
Benjamin Haley
Bettina L Lee
Edward M Bertram
Guy S Salvesen
Irma B Stowe
Jennie R Lill
Jiansheng Wu
Juan Zhang
Karen O'Rourke
P2888
P304
P356
10.1038/NATURE15541
P407
P577
2015-09-16T00:00:00Z