Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression. - Wikidata - awgldk - TriplyDB

Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression.

Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression.

http://www.wikidata.org/entity/Q38843958

about

Sphingosine-1 Phosphate: A New Modulator of Immune Plasticity in the Tumor Microenvironment Therapeutic implications of bioactive sphingolipids: A focus on colorectal cancer.Suppression of c-Myc and RRM2 expression in pancreatic cancer cells by the sphingosine kinase-2 inhibitor ABC294640.Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells.Endogenous Sphingolipid Signaling Pathway Implicated in the Action of Croton membranaceus on the Prostate Gland in BPH Patients.Sphingosine kinase 2 supports the development of BCR/ABL-independent acute lymphoblastic leukemia in mice.In vitro and in vivo anti-tumor and anti-inflammatory capabilities of the novel GSK3 and CKD9 inhibitor ABC1183.A Phase I Study of ABC294640, a First-in-Class Sphingosine Kinase-2 Inhibitor, in Patients with Advanced Solid Tumors.Typical and Atypical Inducers of Lysosomal Cell Death: A Promising Anticancer Strategy

P2860

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P2860

Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression.

http://www.wikidata.org/entity/Q38843958

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

Downregulation of Critical Onc ...... s Prostate Cancer Progression.

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type

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Downregulation of Critical Onc ...... s Prostate Cancer Progression.

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Downregulation of Critical Onc ...... s Prostate Cancer Progression.

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1541-7786.MCR-14-0626

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Molecular Cancer Research

P1476

Downregulation of Critical Onc ...... s Prostate Cancer Progression.

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P2093

Charles D Smith

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Matthew J Schiewer

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Randy S Schrecengost

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Staci N Keller

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P2860

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer

AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer

Integrative genomic profiling of human prostate cancer

Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma.

Discovery and evaluation of inhibitors of human sphingosine kinase.

c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations.

Androgen receptor promotes ligand-independent prostate cancer progression through c-Myc upregulation

Overexpression of C-MYC oncogene in prostate cancer predicts biochemical recurrence.

Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2

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1591-1601

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scholarly article

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10.1158/1541-7786.MCR-14-0626

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12

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13

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Karen E Knudsen

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2015-08-13T00:00:00Z

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