NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy.

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Bromodomain and Extraterminal Protein Inhibitor JQ1 Suppresses Thyroid Tumor Growth in a Mouse Model.Prevalence of Mutations in Discoidin Domain-Containing Receptor Tyrosine Kinase 2 (DDR2) in Squamous Cell Lung Cancers in Korean Patients.

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Q42694831-A30E3D64-B305-473C-8B17-49C8A1F578DB Q50351356-A1493498-0A7E-4421-9B21-9849FDCBFA33

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NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy.

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

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2015年论文

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NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy.

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NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy.

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NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy.

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NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy.

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Chunxiao Xu

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Ellen M Beauchamp

http://www.w3.org/2001/XMLSchema#string

Hideki Terai

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Kevin A Buczkowski

http://www.w3.org/2001/XMLSchema#string

Peter S Hammerman

http://www.w3.org/2001/XMLSchema#string

Yanxi Zhang

http://www.w3.org/2001/XMLSchema#string

Yvonne Y Li

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Selective inhibition of BET bromodomains

Tyrosine 740 phosphorylation of discoidin domain receptor 2 by Src stimulates intramolecular autophosphorylation and Shc signaling complex formation

Expression and mutation analysis of the discoidin domain receptors 1 and 2 in non-small cell lung carcinoma

The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies.

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer.

Cancer statistics, 2013

Comprehensive genomic characterization of squamous cell lung cancers.

Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants

LKB1 modulates lung cancer differentiation and metastasis

Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients.

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2382-2389

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scholarly article

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10.1158/1535-7163.MCT-15-0077

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Kwok Kin Wong

Matthew Meyerson

Hajime Asahina

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2015-07-23T00:00:00Z

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26206333

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jq1

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4596771

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NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy.

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P2860

P2860

NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy.

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P932