Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.

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Structurally simplified biphenyl combretastatin A4 derivatives retain in vitro anti-cancer activity dependent on mitotic arrest Palladium-Catalyzed Enantioselective Redox-Relay Heck Arylation of 1,1-Disubstituted Homoallylic Alcohols.

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Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.

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Synthesis and Biological Evalu ...... alogues of Combretastatin A-4.

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Synthesis and Biological Evalu ...... alogues of Combretastatin A-4.

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Synthesis and Biological Evalu ...... alogues of Combretastatin A-4.

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P1476

Synthesis and Biological Evalu ...... alogues of Combretastatin A-4.

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Chunjiang Liu

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Daiying Zuo

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Huan Qi

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Jiatong Pan

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Jun Sun

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Kai Bao

http://www.w3.org/2001/XMLSchema#string

Lei Chen

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Yingliang Wu

http://www.w3.org/2001/XMLSchema#string

Zhan Wang

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P2860

Design, synthesis, and biological evaluations of 2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoline analogs of combretastatin-A4.

Structural basis for the interaction of tubulin with proteins and drugs that affect microtubule dynamics.

Preparation of dibenzo[e,g]isoindol-1-ones via Scholl-type oxidative cyclization reactions.

Isolation, structure, and synthesis of combretastatins A-1 and B-1, potent new inhibitors of microtubule assembly, derived from Combretum caffrum.

DAT-230, a novel microtubule inhibitor, exhibits potent anti-tumor activity by inducing G2/M phase arrest, apoptosis in vitro and perfusion decrease in vivo to HT-1080.

Pharmaceutical design of antimitotic agents based on combretastatins.

Medicinal chemistry of combretastatin A4: present and future directions.

An overview of tubulin inhibitors that interact with the colchicine binding site

Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors.

Combretastatin a-4 analogs as anticancer agents.

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scholarly article

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10.1111/CBDD.12617

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Wei-Ge Zhang

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2015-07-22T00:00:00Z

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26202587

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Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.

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P2860

P2860

Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.

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P1433

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P577

P698