CIC inactivating mutations identify aggressive subset of 1p19q codeleted gliomas.

CIC inactivating mutations identify aggressive subset of 1p19q codeleted gliomas.

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http://www.wikidata.org/entity/Q38870277
Comparative transcriptome analysis of isogenic cell line models and primary cancers links capicua (CIC) loss to activation of the MAPK signalling cascadeDetection of statistically significant network changes in complex biological networksA new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer.Recurrent CIC Gene Abnormalities in Angiosarcomas: A Molecular Study of 120 Cases With Concurrent Investigation of PLCG1, KDR, MYC, and FLT4 Gene Alterations.Integrated multi-omics analysis of oligodendroglial tumours identifies three subgroups of 1p/19q co-deleted gliomas.Inactivation of Capicua drives cancer metastasisNot all 1p/19q non-codeleted oligodendroglial tumors are astrocytic.Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5.ETV transcriptional upregulation is more reliable than RNA sequencing algorithms and FISH in diagnosing round cell sarcomas with CIC gene rearrangements.Prognostic relevance of genetic alterations in diffuse lower-grade gliomas.Cic Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation.Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.Altered capicua transcriptional repressor gene expression exhibits distinct prognostic value for isocitrate dehydrogenase-mutant oligodendroglial tumors.The Capicua tumor suppressor: a gatekeeper of Ras signaling in development and cancer.Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas.The Transcription Factor ETV5 Mediates BRAFV600E-Induced Proliferation and TWIST1 Expression in Papillary Thyroid Cancer CellsThe Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation
P2860

CIC inactivating mutations identify aggressive subset of 1p19q codeleted gliomas.

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http://www.wikidata.org/entity/Q38870277
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2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年论文
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CIC inactivating mutations identify aggressive subset of 1p19q codeleted gliomas.
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type
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CIC inactivating mutations identify aggressive subset of 1p19q codeleted gliomas.
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CIC inactivating mutations identify aggressive subset of 1p19q codeleted gliomas.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P356
P1433
P1476
CIC inactivating mutations identify aggressive subset of 1p19q codeleted gliomas.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698