Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma
about
Redox Control of Multidrug Resistance and Its Possible Modulation by AntioxidantsAuranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species.Auranofin is a potent suppressor of osteosarcoma metastasis.Development of Inhibitors Targeting Hypoxia-Inducible Factor 1 and 2 for Cancer Therapy.Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer.Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches.Oxidative stress and proteasome inhibitors in multiple myeloma.Multiple myeloma cells' capacity to decompose H2O2 determines lenalidomide sensitivity.The role of ubiquitin-specific protease 14 (USP14) in cell adhesion-mediated drug resistance (CAM-DR) of multiple myeloma cells.Bortezomib-resistance is associated with increased levels of proteasome subunits and apoptosis-avoidanceMetabolic Control of Plasma Cell Differentiation- What We Know and What We Don't Know.Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells.Clinically Evaluated Cancer Drugs Inhibiting Redox Signaling.TrxR1 inhibition overcomes both hypoxia-induced and acquired bortezomib resistance in multiple myeloma through NF-кβ inhibition.Comparative proteomic profiling of refractory/relapsed multiple myeloma reveals biomarkers involved in resistance to bortezomib-based therapy.Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma.The thioredoxin system in breast cancer cell invasion and migrationSmall molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myelomaThe Multifaceted Roles of DJ-1 as an Antioxidant.Thioredoxin promotes survival signaling events under nitrosative/oxidative stress associated with cancer development.Selenoproteins in Tumorigenesis and Cancer Progression.Targeted knockdown of DJ-1 induces multiple myeloma cell death via KLF6 upregulation.Inhibition of thioredoxin activates mitophagy and overcomes adaptive bortezomib resistance in multiple myeloma.Mutant p53 tunes the NRF2-dependent antioxidant response to support survival of cancer cells.Thioredoxin Confers Intrinsic Resistance to Cytostatic Drugs in Human Glioma Cells
P2860
Q26765805-1C8E578C-D824-4E25-B576-9CD38E3BE959Q33829292-6FE34983-9B32-4BEC-B8FA-7C009FB079B3Q36729542-5CB49CE2-B4E6-469A-9E69-213DC2CE41E2Q37723274-9EA39718-50C4-4DFC-92D6-09E4366556F9Q37745339-1472D1A2-2945-413D-8A57-76E26A82B364Q38645501-5BB88A48-9CB5-4946-B6EC-7A908D101193Q38717135-E05751C0-8729-4A93-8FA3-425E4E26D44AQ38724074-716C9668-247C-43FC-B61C-7C2F07D208B4Q38734491-C2312FF7-E70E-4D2C-A853-FDE1DC3B1D3DQ38739048-6573590D-B71F-4FE5-A6EB-FBEAAAD6BCB9Q38748145-AC863E14-CB80-4F9D-9947-FAAB65D62864Q38765278-AB61265A-2629-4C0E-BDC6-AFADD39BDA2BQ38777221-690F7950-E615-4DCE-9A38-FBD3EFCAD082Q38805723-B99DCEE0-81D1-4A91-9980-B2E936BE731AQ39487681-C712F865-8D5B-426D-958B-D81708BC15FDQ41882913-0F418A18-D3FB-4891-B336-6782AD987B51Q42003950-2B578F75-141F-44A0-8477-9CEAE1F88782Q42371593-9744F588-2395-4DB2-9212-1301F4E82772Q46259811-8DFF416F-1227-425B-B0C4-DFFF756F4EEFQ46305740-8CA7A6C5-B99A-4566-BC15-7311E33EEA44Q47622822-3ECF1A45-B639-4CAA-A691-A3D8AB8805BEQ48955308-BC155190-0290-49DD-A5E7-2BE72AFE188FQ50318733-063AD313-D2A2-42E3-B327-3F1980C8DF9EQ55281959-F0124011-13AF-4ABC-A3E1-F6A8CA7AD20EQ59134245-1B3EC367-3CBD-4C1C-BED0-19F61CA8E773
P2860
Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma
@en
type
label
Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma
@en
prefLabel
Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma
@en
P2860
P50
P356
P1433
P1476
Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma
@en
P2093
Maneet Bhatia
Slavica Vuckovic
P2860
P304
15410-15424
P356
10.18632/ONCOTARGET.3795
P407
P577
2015-06-01T00:00:00Z