PDX1 binds and represses hepatic genes to ensure robust pancreatic commitment in differentiating human embryonic stem cells.
about
Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling.Pdx1 regulates pancreas tubulogenesis and E-cadherin expression.Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia.Adult human pancreas-derived cells expressing stage-specific embryonic antigen 4 differentiate into Sox9-expressing and Ngn3-expressing pancreatic ducts in vivo.An arduous journey from human pluripotent stem cells to functional pancreatic β cells.Combinations of Activin A or Nicotinamide with the Pancreatic Transcription Factor PDX1 Support Differentiation of Human Amnion Epithelial Cells Toward a Pancreatic Lineage.The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1.Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.
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Q30313776-2377A02B-2577-42DB-97EF-EC55FAA232CBQ36497262-3385ED08-DE87-4CB3-B613-E37FEA527B5BQ36678758-0B61C571-5E1E-4CDA-9426-9D78240632A0Q37408922-0D876070-6382-404F-8984-A13FD325F960Q38557710-A6AB6002-D484-4465-AC3E-B7EC8FD9B20DQ45061718-BA11EAB0-FAD3-4AD2-9244-1B6E4166C003Q46443249-435CC2CF-FDA3-4263-A925-E5E92BB4B5A3Q48181784-92D499EC-616F-45D5-8E98-FC186B98E49CQ49358937-6BCBCA81-3E99-40FE-9A90-1E1426BC7436
P2860
PDX1 binds and represses hepatic genes to ensure robust pancreatic commitment in differentiating human embryonic stem cells.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
PDX1 binds and represses hepat ...... ng human embryonic stem cells.
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type
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PDX1 binds and represses hepat ...... ng human embryonic stem cells.
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prefLabel
PDX1 binds and represses hepat ...... ng human embryonic stem cells.
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P2093
P2860
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PDX1 binds and represses hepat ...... ng human embryonic stem cells.
@en
P2093
Christopher V E Wright
Ee Kim Tan
Lawrence W Stanton
Norihiro Tsuneyoshi
Shawn Hoon
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P304
P356
10.1016/J.STEMCR.2015.02.015
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2015-04-02T00:00:00Z