D-2-Hydroxyglutarate does not mimic all the IDH mutation effects, in particular the reduced etoposide-triggered apoptosis mediated by an alteration in mitochondrial NADH.
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Molecular Pathways: Isocitrate Dehydrogenase Mutations in Cancer.A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in gliomaThe Diagnostic Use of Immunohistochemical Surrogates for Signature Molecular Genetic Alterations in Gliomas.Glioma Subclassifications and Their Clinical Significance.Molecular mechanisms of isocitrate dehydrogenase 1 (IDH1) mutations identified in tumors: The role of size and hydrophobicity at residue 132 on catalytic efficiency.A high 18F-FDOPA uptake is associated with a slow growth rate in diffuse Grade II-III gliomas.The role of mutant IDH1 and IDH2 inhibitors in the treatment of acute myeloid leukemia.Is the information provided by amino acid PET radiopharmaceuticals clinically equivalent in gliomas?D-2-Hydroxyglutarate Is Necessary and Sufficient for Isocitrate Dehydrogenase 1 Mutant-Induced MIR148A Promoter Methylation.A high-throughput analysis of the IDH1(R132H) protein expression in pituitary adenomas.
P2860
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P2860
D-2-Hydroxyglutarate does not mimic all the IDH mutation effects, in particular the reduced etoposide-triggered apoptosis mediated by an alteration in mitochondrial NADH.
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2015 nî lūn-bûn
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2015年の論文
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name
D-2-Hydroxyglutarate does not ...... eration in mitochondrial NADH.
@en
type
label
D-2-Hydroxyglutarate does not ...... eration in mitochondrial NADH.
@en
prefLabel
D-2-Hydroxyglutarate does not ...... eration in mitochondrial NADH.
@en
P2093
P2860
P356
P1476
D-2-Hydroxyglutarate does not ...... teration in mitochondrial NADH
@en
P2093
A Nadaradjane
C Pecqueur
F M Vallette
P2860
P356
10.1038/CDDIS.2015.13
P50
P577
2015-03-26T00:00:00Z