H-ras distribution and signaling in plasma membrane microdomains are regulated by acylation and deacylation events.
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Individual S-acylated cysteines differentially contribute to H-Ras endomembrane trafficking and acylation/deacylation cycles.Defined spatiotemporal features of RAS-ERK signals dictate cell fate in MCF-7 mammary epithelial cells.Regulation of H-Ras-driven MAPK signaling, transformation and tumorigenesis, but not PI3K signaling and tumor progression, by plasma membrane microdomains.How to Target Activated Ras Proteins: Direct Inhibition vs. Induced Mislocalization.ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization.Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and AutoimmunityA Lipid-Anchored NAC Transcription Factor Is Translocated into the Nucleus and Activates Glyoxalase I Expression during Drought Stress.The role of S-acylation in protein trafficking.Wogonoside induces depalmitoylation and translocation of PLSCR1 and N-RAS in primary acute myeloid leukaemia cells.Analysis of Ras/ERK Compartmentalization by Subcellular Fractionation.Farnesyltransferase Inhibition Exacerbates Eosinophilic Inflammation and Airway Hyperreactivity in Mice with Experimental Asthma: The Complex Roles of Ras GTPase and Farnesylpyrophosphate in Type 2 Allergic Inflammation.The microdomain-organizing protein MPP1 is required for insulin-stimulated activation of H-Ras.
P2860
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P2860
H-ras distribution and signaling in plasma membrane microdomains are regulated by acylation and deacylation events.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
H-ras distribution and signali ...... lation and deacylation events.
@en
type
label
H-ras distribution and signali ...... lation and deacylation events.
@en
prefLabel
H-ras distribution and signali ...... lation and deacylation events.
@en
P2093
P2860
P356
P1476
H-ras distribution and signali ...... lation and deacylation events.
@en
P2093
Ana Herrero
Lorena Agudo-Ibáñez
Mariano Barbacid
P2860
P304
P356
10.1128/MCB.01398-14
P407
P50
P577
2015-03-16T00:00:00Z