Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB-siRNA conjugates. - Wikidata - awgldk - TriplyDB

Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB-siRNA conjugates.

Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB-siRNA conjugates.

http://www.wikidata.org/entity/Q38924311

about

Cell Penetrating Peptide Conjugated Chitosan for Enhanced Delivery of Nucleic Acid Knocking down disease: a progress report on siRNA therapeutics Antibody-siRNA conjugates: drugging the undruggable for anti-leukemic therapy.A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery.A novel excision selection method for isolation of antibodies binding antigens expressed specifically by rare cells in tissue sections A specific aptamer-cell penetrating peptides complex delivered siRNA efficiently and suppressed prostate tumor growth in vivo.Design of a platform technology for systemic delivery of siRNA to tumours using rolling circle transcription.Antibody h-R3-dendrimer mediated siRNA has excellent endosomal escape and tumor targeted delivery ability, and represents efficient siPLK1 silencing and inhibition of cell proliferation, migration and invasion.The delivery of therapeutic oligonucleotides Direct Pharmacological Inhibition of β-Catenin by RNA Interference in Tumors of Diverse Origin Cholesterol-Containing Nuclease-Resistant siRNA Accumulates in Tumors in a Carrier-free Mode and Silences MDR1 Gene.Delivery strategies and potential targets for siRNA in major cancer types Functional peptides for siRNA delivery.The chemical evolution of oligonucleotide therapies of clinical utility.The Race of 10 Synthetic RNAi-Based Drugs to the Pharmaceutical Market.Cytosolic delivery of siRNA by ultra-high affinity dsRNA binding proteins.Delivery of gene targeting siRNAs to breast cancer cells using a multifunctional peptide complex that promotes both targeted delivery and endosomal release.RNA interference for glioblastoma therapy: Innovation ladder from the bench to clinical trials.Targeted Delivery of siRNA Therapeutics to Malignant Tumors.A Poly(Propyleneimine) Dendrimer-Based Polyplex-System for Single-Chain Antibody-Mediated Targeted Delivery and Cellular Uptake of SiRNA.The Role of micro RNAs in Breast Cancer Metastasis: Preclinical Validation and Potential Therapeutic Targets.Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo.Antibody-Antisense Oligonucleotide Conjugate Downregulates a Key Gene in Glioblastoma Stem Cells.Current Challenges in Delivery and Cytosolic Translocation of Therapeutic RNAs.

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Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB-siRNA conjugates.

http://www.wikidata.org/entity/Q38924311

description

2014 nî lūn-bûn

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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2014年學術文章

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2014年學術文章

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name

Systematic evaluation of antib ...... m of THIOMAB-siRNA conjugates.

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Systematic evaluation of antib ...... m of THIOMAB-siRNA conjugates.

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Systematic evaluation of antib ...... m of THIOMAB-siRNA conjugates.

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Nucleic Acids Research

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Systematic evaluation of antib ...... rm of THIOMAB-siRNA conjugates

@en

P2093

Anja van Brabant Smith

http://www.w3.org/2001/XMLSchema#string

Christian W Siebel

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Christopher Nelson

http://www.w3.org/2001/XMLSchema#string

David Davis

http://www.w3.org/2001/XMLSchema#string

Devin Leake

http://www.w3.org/2001/XMLSchema#string

Dwight Barnes

http://www.w3.org/2001/XMLSchema#string

Joshua Tanguay

http://www.w3.org/2001/XMLSchema#string

Julie Gesch

http://www.w3.org/2001/XMLSchema#string

Richard Vandlen

http://www.w3.org/2001/XMLSchema#string

Shang-Fan Yu

http://www.w3.org/2001/XMLSchema#string

P2860

T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

Current prospects for RNA interference-based therapies

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

Expression profiling reveals off-target gene regulation by RNAi

Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin

Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells.

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1189-1203

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scholarly article

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10.1093/NAR/GKU1362

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2

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43

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Trinna L Cuellar

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2014-12-30T00:00:00Z

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25550431

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4333408

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