High prevalence of quintuple mutant dhps/dhfr genes in Plasmodium falciparum infections seven years after introduction of sulfadoxine and pyrimethamine as first line treatment in Malawi.
about
Association of house spraying with suppressed levels of drug resistance in ZimbabweMarked reduction in prevalence of malaria parasitemia and anemia in HIV-infected pregnant women taking cotrimoxazole with or without sulfadoxine-pyrimethamine intermittent preventive therapy during pregnancy in MalawiA randomized controlled pilot trial of azithromycin or artesunate added to sulfadoxine-pyrimethamine as treatment for malaria in pregnant womenMultiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malariaSulfadoxine resistance in Plasmodium vivax is associated with a specific amino acid in dihydropteroate synthase at the putative sulfadoxine-binding site.Seasonal distribution of anti-malarial drug resistance alleles on the island of Sumba, Indonesia.High resolution melting: a useful field-deployable method to measure dhfr and dhps drug resistance in both highly and lowly endemic Plasmodium populations.Tracing the origins and signatures of selection of antifolate resistance in island populations of Plasmodium falciparumFive years of large-scale dhfr and dhps mutation surveillance following the phased implementation of artesunate plus sulfadoxine-pyrimethamine in Maputo Province, Southern Mozambique.Mutations associated with sulfadoxine-pyrimethamine and chlorproguanil resistance in Plasmodium falciparum isolates from Blantyre, MalawiDrug coverage in treatment of malaria and the consequences for resistance evolution--evidence from the use of sulphadoxine/pyrimethamine.Spontaneous mutations in the Plasmodium falciparum sarcoplasmic/ endoplasmic reticulum Ca2+-ATPase (PfATP6) gene among geographically widespread parasite populations unexposed to artemisinin-based combination therapies.Evaluation of prevalence's of pfdhfr and pfdhps mutations in Angola.High prevalence of drug-resistance mutations in Plasmodium falciparum and Plasmodium vivax in southern Ethiopia.High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese childrenDrug resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum malaria in Mlimba, TanzaniaMolecular monitoring of resistant dhfr and dhps allelic haplotypes in Morogoro and Mvomero districts in south eastern Tanzania.Drug resistance maps to guide intermittent preventive treatment of malaria in African infants.Limited geographical origin and global spread of sulfadoxine-resistant dhps alleles in Plasmodium falciparum populations.The evolution of pyrimethamine resistant dhfr in Plasmodium falciparum of south-eastern Tanzania: comparing selection under SP alone vs SP+artesunate combination.Molecular surveillance of drug-resistance associated mutations of Plasmodium falciparum in south-west TanzaniaIndependent evolution of pyrimethamine resistance in Plasmodium falciparum isolates in Melanesia.Media, health workers, and policy makers' relationship and their impact on antimalarial policy adoption: a population genetics perspective.Adaptive evolution and fixation of drug-resistant Plasmodium falciparum genotypes in pregnancy-associated malaria: 9-year results from the QuEERPAM studyMalaria chemoprophylaxis: when should we use it and what are the options?Effectiveness of intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy on maternal and birth outcomes in Machinga district, Malawi.Alterations in Plasmodium falciparum genetic structure two years after increased malaria control efforts in western Kenya.High prevalence of mutation in the Plasmodium falciparum dhfr and dhps genes in field isolates from Sabah, Northern Borneo.Detection of the dihydrofolate reductase-164L mutation in Plasmodium falciparum infections from Malawi by heteroduplex tracking assay.Prevalence of pfmdr1, pfcrt, pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, AngolaPolymorphism in dhfr/dhps genes, parasite density and ex vivo response to pyrimethamine in Plasmodium falciparum malaria parasites in Thies, Senegal.Characteristics of genetic hitchhiking around dihydrofolate reductase gene associated with pyrimethamine resistance in Plasmodium falciparum isolates from India.Plasmodium falciparum: higher incidence of molecular resistance markers for sulphadoxine than for pyrimethamine in Kasangati, Uganda.High frequency of the genetic polymorphisms associated with sulfadoxine-pyrimethamine resistance, among Plasmodium falciparum isolates from São Tomé and Príncipe, West Africa.Epidemiology of drug-resistant malaria in Republic of Congo: using molecular evidence for monitoring antimalarial drug resistance combined with assessment of antimalarial drug use.Mutational analysis of Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in the interior division of Sabah, MalaysiaPlasmodium falciparum isolates in India exhibit a progressive increase in mutations associated with sulfadoxine-pyrimethamine resistance.Sulfadoxine-pyrimethamine for uncomplicated falciparum malaria: sulfadoxine-pyrimethamine is not working in Malawi.
P2860
Q24803104-B9A4E7C9-B0DF-47B5-AAAD-8FFE0404EEDAQ28387497-F0E74FA9-8EB8-4014-8989-58FA15774BC7Q28469347-4DE98402-3F81-4177-98D6-430CF18DC787Q28475195-8507F932-9C11-4165-8EEB-35F7BC544C83Q31064063-75027DFB-1074-4142-902C-49133F420EA7Q33507449-7FFC09FE-BCE0-4409-9DC4-9E7622CDEF3AQ33576274-11C486E9-A526-4B81-80F1-5259A0ADAACCQ33599358-4BC9CBF4-6489-4B53-9BDC-C08F9A7DAC7BQ33817503-EC8F86AC-3C28-46D5-8B83-95A31FE98D0EQ33935361-3552D77D-E208-4480-B695-96F6A0B12AB2Q34014169-04371525-6AF5-423E-B334-B4CC06A5F102Q34483513-A67DC28B-B3CF-4616-8FF7-F8F75BAE7020Q34576841-8C2DBCFB-53CD-4E33-BEBB-AD6689568494Q34881204-58F90A0D-2B92-4DE8-92C6-DAB738AE042EQ35038632-E3547F8E-8C0B-453E-BD35-9582DF78FBC5Q35129708-7249103B-0940-4C09-9462-8A03A18F78BAQ35171924-2C30C811-E4E4-427B-9237-AECCF3DAD3A2Q35228689-21B69C30-D02B-4587-B009-6AEE1F1DDF62Q35532863-A82466A6-7C84-4451-989E-D66C3036F7B9Q35541212-36D27EE3-5388-441D-A8D7-E20DD2ED96CBQ35610058-5F55FA71-E376-4C66-A0C0-D88D135CC8A5Q35647764-6E2F0622-4B1F-475C-AB57-CBB9FA8E4771Q35755266-48FEB816-1335-4293-892C-B97E2E4E4E1BQ35802773-0A6B1B1B-E795-4AAB-9871-08BEB1CF1938Q35917341-5878FFEA-4EAA-4D64-BEBF-B1722EA89164Q36466975-E4C2314F-69C4-4FF5-81C3-5D8610DBC059Q36523046-B2902CBC-8453-4BC2-AC82-1FE5BB499BDBQ36996772-0065B97A-F6AC-4234-8B94-6C78DBB3BCA2Q37012863-3EACC5BD-B3F8-46F4-B214-06BB503A71C1Q37035250-249EDD28-BF74-4203-89B9-A2C6AE605A14Q37390524-C8850CBC-DA68-4AC1-B2F5-A11849241D26Q37450805-14C09B7F-FFF1-497D-8D8D-F54517E3FEB0Q38880836-EA1F8D18-5569-45A0-B53A-5FF9EAE9929AQ38955978-C1D4A9F4-402B-4682-8995-9FBBBDD5661BQ39731224-C82B6B30-92F3-483A-9846-34222308DCEAQ39831818-454B40AD-23AB-4D1D-94F0-B61B3F17809AQ40622316-E416E230-56D6-4269-8D4A-FEA347444ED7Q43240986-00B353AA-AD94-4FC9-817F-8A6D348CCA00
P2860
High prevalence of quintuple mutant dhps/dhfr genes in Plasmodium falciparum infections seven years after introduction of sulfadoxine and pyrimethamine as first line treatment in Malawi.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
High prevalence of quintuple m ...... irst line treatment in Malawi.
@en
type
label
High prevalence of quintuple m ...... irst line treatment in Malawi.
@en
prefLabel
High prevalence of quintuple m ...... irst line treatment in Malawi.
@en
P2093
P921
P1433
P1476
High prevalence of quintuple m ...... first line treatment in Malawi
@en
P2093
A Björkman
N Takahashi
T Kobayakawa
Y Bergqvist
Y Moriyama
P304
P356
10.1016/S0001-706X(02)00264-4
P577
2003-03-01T00:00:00Z