The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer. - Wikidata - awgldk - TriplyDB

The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer.

The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer.

http://www.wikidata.org/entity/Q38930113

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Regulation of cellular redox signaling by matricellular proteins in vascular biology, immunology, and cancer Mithramycin-loaded mPEG-PLGA nanoparticles exert potent antitumor efficacy against pancreatic carcinoma.New Strategies Using Antibody Combinations to Increase Cancer Treatment Effectiveness.A function-blocking CD47 antibody modulates extracellular vesicle-mediated intercellular signaling between breast carcinoma cells and endothelial cells.Genetic variation of human neutrophil Fcγ receptors and SIRPα in antibody-dependent cellular cytotoxicity towards cancer cells.Tumor-associated myeloid cells: new understandings on their metabolic regulation and their influence in cancer immunotherapy.Anti-human SIRPα antibody is a new tool for cancer immunotherapy.Introduction to checkpoint inhibitors and cancer immunotherapy.How many diseases is triple negative breast cancer: the protagonism of the immune microenvironment.ALX148 blocks CD47 and enhances innate and adaptive antitumor immunity with a favorable safety profile Autochthonous murine models for the study of smoker and never-smoker associated lung cancers

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The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer.

http://www.wikidata.org/entity/Q38930113

description

2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年學術文章

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The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer.

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The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer.

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The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer.

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Immunological Reviews

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The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer.

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Hanke L Matlung

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Katka Szilagyi

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Neil A Barclay

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Timo K van den Berg

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P2860

Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47

Human herpesvirus 8 K14 protein mimics CD200 in down-regulating macrophage activation through CD200 receptor

Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response

Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies.

Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy

Endothelial CD47 interaction with SIRPgamma is required for human T-cell transendothelial migration under shear flow conditions in vitro.

Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

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145-164

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10.1111/IMR.12527

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1

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276

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