SYK is a candidate kinase target for the treatment of advanced prostate cancer.
about
Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugsEvolutionary divergence of the vertebrate TNFAIP8 gene family: Applying the spotted gar orthology bridge to understand ohnolog loss in teleostsLongitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA-/lo castration-resistant cells.Inhibition of signaling between human CXCR4 and zebrafish ligands by the small molecule IT1t impairs the formation of triple-negative breast cancer early metastases in a zebrafish xenograft modelER maleate is a novel anticancer agent in oral cancer: implications for cancer therapy.Gene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line.CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer.Central role of PI3K-SYK interaction in fibrinogen-induced lamellipodia and filopodia formation in platelets.Enzalutamide inhibits testosterone-induced growth of human prostate cancer xenografts in zebrafish and can induce bradycardia.Activated spleen tyrosine kinase promotes malignant progression of oral squamous cell carcinoma via mTOR/S6 signaling pathway in an ERK1/2-independent manner.SYK-targeted dendritic cell-mediated cytotoxic T lymphocytes enhance the effect of immunotherapy on retinoblastoma.Aberrant SYK Kinase Signaling Is Essential for Tumorigenesis Induced by TSC2 Inactivation.Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway.Fishing for cures: The alLURE of using zebrafish to develop precision oncology therapies.Crystal Structures of Spleen Tyrosine Kinase in Complex with Two Novel 4-Aminopyrido[4,3-d] Pyrimidine Derivative Inhibitors.Identification of spleen tyrosine kinase as a potential therapeutic target for esophageal squamous cell carcinoma using reverse phase protein arrays.Prognostic value of spleen tyrosine kinase in human solid tumors.
P2860
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P2860
SYK is a candidate kinase target for the treatment of advanced prostate cancer.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
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2014年學術文章
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name
SYK is a candidate kinase target for the treatment of advanced prostate cancer.
@en
type
label
SYK is a candidate kinase target for the treatment of advanced prostate cancer.
@en
prefLabel
SYK is a candidate kinase target for the treatment of advanced prostate cancer.
@en
P2093
P50
P1433
P1476
SYK is a candidate kinase target for the treatment of advanced prostate cancer
@en
P2093
A Marije M Hoogland
Annemarie Lekkerkerker
B Ewa Snaar-Jagalska
Bob van de Water
Geert J L H van Leenders
Guido Jenster
Hans de Bont
Jiangling Xiong
Richard Janssen
Shuning He
P304
P356
10.1158/0008-5472.CAN-14-0629
P407
P577
2014-11-11T00:00:00Z