The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure.
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Lipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling Pathway.GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary.Alteration of protein prenylation promotes spermatogonial differentiation and exhausts spermatogonial stem cells in newborn miceThe long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy.Inhibition of farnesyl pyrophosphate synthase improves pressure overload induced chronic cardiac remodelingOverexpression of geranylgeranyl diphosphate synthase contributes to tumour metastasis and correlates with poor prognosis of lung adenocarcinoma.GGPPS-mediated Rab27A geranylgeranylation regulates β cell dysfunction during type 2 diabetes development by affecting insulin granule docked pool formation.GGPPS deficiency aggravates CCl4-induced liver injury by inducing hepatocyte apoptosis.
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The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure.
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2015 nî lūn-bûn
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The alteration of protein pren ...... eads to chronic heart failure.
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The alteration of protein pren ...... eads to chronic heart failure.
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prefLabel
The alteration of protein pren ...... eads to chronic heart failure.
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P2093
P2860
P356
P1476
The alteration of protein pren ...... leads to chronic heart failure
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Chao-Jun Li
Fei-Yan Pan
Ning-Wei Zhao
Zhong Chen
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P304
P356
10.1002/PATH.4480
P50
P577
2015-01-07T00:00:00Z