Chroman-4-one- and chromone-based sirtuin 2 inhibitors with antiproliferative properties in cancer cells.
about
Sirtuin functions and modulation: from chemistry to the clinicCharacterization of Trypanosoma cruzi Sirtuins as Possible Drug Targets for Chagas Disease.A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity.Unprecedented formation of 3-(tetrahydrofuran-2-yl)-4H-chromen-4-one in a reaction between 3,3a-dihydro-9H-furo[3,4-b]chromen-9-one and malononitrile.The Current State of NAD(+) -Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets.Chromatin determinants impart camptothecin sensitivity.New chroman-4-one/thiochroman-4-one derivatives as potential anticancer agents.Thienopyrimidinone Based Sirtuin-2 (SIRT2)-Selective Inhibitors Bind in the Ligand Induced Selectivity Pocket.New chemical tools for probing activity and inhibition of the NAD+-dependent lysine deacylase sirtuin 2.A highly enantioselective access to chiral chromanones and thiochromanones via copper-catalyzed asymmetric conjugated reduction of chromones and thiochromones.
P2860
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P2860
Chroman-4-one- and chromone-based sirtuin 2 inhibitors with antiproliferative properties in cancer cells.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
@zh-sg
2014年學術文章
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2014年學術文章
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2014年學術文章
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name
Chroman-4-one- and chromone-ba ...... ve properties in cancer cells.
@en
type
label
Chroman-4-one- and chromone-ba ...... ve properties in cancer cells.
@en
prefLabel
Chroman-4-one- and chromone-ba ...... ve properties in cancer cells.
@en
P2093
P50
P356
P1476
Chroman-4-one- and chromone-ba ...... ive properties in cancer cells
@en
P2093
Elina M Jarho
Karin Engen
Kristina Luthman
Marcus Malo
Maria Fridén-Saxin
Tina Seifert
P304
P356
10.1021/JM500930H
P407
P577
2014-12-02T00:00:00Z