Design and optimization of novel hydroxamate-based histone deacetylase inhibitors of Bis-substituted aromatic amides bearing potent activities against tumor growth and metastasis.
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Discovery and Optimization of N-Substituted 2-(4-pyridinyl)thiazole carboxamides against Tumor Growth through Regulating Angiogenesis Signaling Pathways.A hybrid of thiazolidinone with the hydroxamate scaffold for developing novel histone deacetylase inhibitors with antitumor activities.Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model.Inhibition of histone deacetylases sensitizes EGF receptor-TK inhibitor-resistant non-small-cell lung cancer cells to erlotinib in vitro and in vivo.Inhibition of HDACs-EphA2 Signaling Axis with WW437 Demonstrates Promising Preclinical Antitumor Activity in Breast Cancer.Metastatic and triple-negative breast cancer: challenges and treatment options
P2860
Design and optimization of novel hydroxamate-based histone deacetylase inhibitors of Bis-substituted aromatic amides bearing potent activities against tumor growth and metastasis.
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2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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2014年學術文章
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2014年學術文章
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name
Design and optimization of nov ...... t tumor growth and metastasis.
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type
label
Design and optimization of nov ...... t tumor growth and metastasis.
@en
prefLabel
Design and optimization of nov ...... t tumor growth and metastasis.
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P2093
P356
P1476
Design and optimization of nov ...... st tumor growth and metastasis
@en
P2093
Beier Jiang
Feifei Yang
Haigang Wu
Jingjie Li
Mingyao Liu
P304
P356
10.1021/JM5012148
P407
P50
P577
2014-11-12T00:00:00Z