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PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1.The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets.A novel Alzheimer's disease drug candidate targeting inflammation and fatty acid metabolism.The biosynthesis of nitrous oxide in the green alga Chlamydomonas reinhardtii.Role of Eukaryotic Initiation Factors during Cellular Stress and Cancer ProgressionImpact of Yoga and Meditation on Cellular Aging in Apparently Healthy Individuals: A Prospective, Open-Label Single-Arm Exploratory Study.Functional inhibition of acid sphingomyelinase by Fluphenazine triggers hypoxia-specific tumor cell death.PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR)ER stress and the unfolded protein response in neurodegeneration.The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine.Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals.ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner.Endoplasmic Reticulum Protein Quality Control Failure in Myelin Disorders.Integrated Stress Response as a Therapeutic Target for CNS Injuries.Regulation of the unfolded protein response by noncoding RNA.Drug repurposing to target proteostasis and prevent neurodegeneration: accelerating translational efforts.Dysregulated IL-1β Secretion in Autoinflammatory Diseases: A Matter of Stress?D-serine, a novel uremic toxin, induces senescence in human renal tubular cells via GCN2 activation.Proteostasis disturbance in amyotrophic lateral sclerosis.An emergency brake for protein synthesis.PKR involvement in Alzheimer's diseaseOncogenic FLT3-ITD supports autophagy via ATF4 in acute myeloid leukemia.The transcription factor CHOP, an effector of the integrated stress response, is required for host sensitivity to the fungal intracellular pathogen Histoplasma capsulatum.The CDK inhibitor p21 is a novel target gene of ATF4 and contributes to cell survival under ER stress.The mitochondrial UPR: mechanisms, physiological functions and implications in ageing.The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate.Putting It Together: Sleep Apnea, the Integrated Stress Response, and Metabolic Dysfunction.DDX3 regulates endoplasmic reticulum stress-induced ATF4 expression.Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT.Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for Dystonia.Oxygen-Sensitive Remodeling of Central Carbon Metabolism by Archaic eIF5B.Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation.Lower temperatures reduce type I interferon activity and promote alphaviral arthritis.Please do not recycle! Translation reinitiation in microbes and higher eukaryotes.(off)Targeting UPR signaling: the race toward intervening ER proteostasis.ER stress in skeletal muscle remodeling and myopathies.Transcription Factor C/EBP Homologous Protein in Health and Diseases.A Unique ISR Program Determines Cellular Responses to Chronic Stress.MAPK inhibitors induce serine peptidase inhibitor Kazal type 1 (SPINK1) secretion in BRAF V600E-mutant colorectal adenocarcinoma.HRI coordinates translation by eIF2αP and mTORC1 to mitigate ineffective erythropoiesis in mice during iron deficiency.
P2860
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P2860
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
The integrated stress response.
@en
type
label
The integrated stress response.
@en
prefLabel
The integrated stress response.
@en
P2860
P50
P356
P1433
P1476
The integrated stress response
@en
P2093
Karolina Pakos-Zebrucka
Mila Ljujic
P2860
P304
P356
10.15252/EMBR.201642195
P577
2016-09-14T00:00:00Z