Latest Advances Towards Ras Inhibition: A Medicinal Chemistry Perspective.

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Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling.

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Latest Advances Towards Ras Inhibition: A Medicinal Chemistry Perspective.

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

@zh-tw

2016年论文

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2016年论文

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2016年论文

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Latest Advances Towards Ras Inhibition: A Medicinal Chemistry Perspective.

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Latest Advances Towards Ras Inhibition: A Medicinal Chemistry Perspective.

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Latest Advances Towards Ras Inhibition: A Medicinal Chemistry Perspective.

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P1476

Latest Advances Towards Ras Inhibition: A Medicinal Chemistry Perspective

@en

P2093

Carl F Nising

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Developing irreversible inhibitors of the protein kinase cysteinome

K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions

Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State

Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods

Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials.

Osimertinib: First Global Approval.

Targeting RAS signalling pathways in cancer therapy

Discovery of a clinical stage multi-kinase inhibitor sodium (E)-2-{2-methoxy-5-[(2',4',6'-trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na): synthesis, structure-activity relationship, and biological activity

RAS oncogenes: weaving a tumorigenic web

Preclinical pharmacokinetic and pharmacodynamic evaluation of novel anticancer agents, ON01910.Na (Rigosertib, Estybon™) and ON013105, for brain tumor chemotherapy

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15982-15988

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scholarly article

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10.1002/ANIE.201608270

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English

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Lars Wortmann

Brice Sautier

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2016-11-22T00:00:00Z

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27635522

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Latest Advances Towards Ras Inhibition: A Medicinal Chemistry Perspective.

about

P2860

P2860

Latest Advances Towards Ras Inhibition: A Medicinal Chemistry Perspective.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698