Lassa virus nucleoprotein mutants generated by reverse genetics induce a robust type I interferon response in human dendritic cells and macrophages
about
Advanced vaccine candidates for Lassa feverInhibition of Innate Immune Responses Is Key to Pathogenesis by ArenavirusesMultifunctional nature of the arenavirus RING finger protein Z.Lymphocytic Choriomeningitis Virus Differentially Affects the Virus-Induced Type I Interferon Response and Mitochondrial Apoptosis Mediated by RIG-I/MAVS.Pathogenic Old World arenaviruses inhibit TLR2/Mal-dependent proinflammatory cytokines in vitroThe search for animal models for Lassa fever vaccine developmentVaccine Platforms to Control Arenaviral Hemorrhagic FeversArenavirus reverse genetics for vaccine developmentInnate immune response to arenaviral infection: a focus on the highly pathogenic New World hemorrhagic arenaviruses.Production of CXC and CC chemokines by human antigen-presenting cells in response to Lassa virus or closely related immunogenic viruses, and in cynomolgus monkeys with lassa fever.Host cell factors as antiviral targets in arenavirus infection.Immune responses and Lassa virus infection.Current drug discovery strategies against arenavirus infections.Human hemorrhagic Fever causing arenaviruses: molecular mechanisms contributing to virus virulence and disease pathogenesis.Novel drug discovery approaches for treating arenavirus infections.In vitro and in vivo characterizations of pichinde viral nucleoprotein exoribonuclease functions.Inhibition of arenavirus by A3, a pyrimidine biosynthesis inhibitor.A Case of Human Lassa Virus Infection With Robust Acute T-Cell Activation and Long-Term Virus-Specific T-Cell Responses.Exonuclease domain of the Lassa virus nucleoprotein is critical to avoid RIG-I signaling and to inhibit the innate immune response.The exonuclease domain of Lassa virus nucleoprotein is involved in antigen-presenting-cell-mediated NK cell responses.Arenavirus nucleoproteins prevent activation of nuclear factor kappa B.Determining the Virus Life-Cycle Stage Blocked by an Antiviral.Immunosuppressive arenaviral exoribonuclease.A vaccine platform against arenaviruses based on a recombinant hyper-attenuated Mopeia virus expressing heterologous glycoproteins.Use of a Scalable Replicon-Particle Vaccine to Protect Against Lethal Lassa Virus Infection in the Guinea Pig ModelDDX3 suppresses type I interferons and favors viral replication during Arenavirus infection
P2860
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P2860
Lassa virus nucleoprotein mutants generated by reverse genetics induce a robust type I interferon response in human dendritic cells and macrophages
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Lassa virus nucleoprotein muta ...... endritic cells and macrophages
@en
type
label
Lassa virus nucleoprotein muta ...... endritic cells and macrophages
@en
prefLabel
Lassa virus nucleoprotein muta ...... endritic cells and macrophages
@en
P2093
P2860
P50
P356
P1433
P1476
Lassa virus nucleoprotein muta ...... endritic cells and macrophages
@en
P2093
Laure Diancourt
Michèle Bouloy
Noel Tordo
Valérie Caro
P2860
P304
12093-12097
P356
10.1128/JVI.00429-11
P407
P577
2011-08-31T00:00:00Z