Reversal of phenotypes of cellular senescence by pan-mTOR inhibition.
about
Erythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life ExpectancyFrom rapalogs to anti-aging formula.mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancerGerosuppression by pan-mTOR inhibitors.Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer.Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence.The bright side of reactive oxygen species: lifespan extension without cellular demise.Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells.Chronic exposure to rapamycin and episodic serum starvation modulate ageing of human fibroblasts in vitro.While reinforcing cell cycle arrest, rapamycin and Torins suppress senescence in UVA-irradiated fibroblasts.mTOR pathway activation drives lung cell senescence and emphysema.Blocking negative effects of senescence in human skin fibroblasts with a plant extract.The tumor suppressor menin prevents effector CD8 T-cell dysfunction by targeting mTORC1-dependent metabolic activationmTORC Inhibitors as Broad-Spectrum Therapeutics for Age-Related Diseases
P2860
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P2860
Reversal of phenotypes of cellular senescence by pan-mTOR inhibition.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Reversal of phenotypes of cellular senescence by pan-mTOR inhibition.
@en
type
label
Reversal of phenotypes of cellular senescence by pan-mTOR inhibition.
@en
prefLabel
Reversal of phenotypes of cellular senescence by pan-mTOR inhibition.
@en
P2860
P356
P1433
P1476
Reversal of phenotypes of cellular senescence by pan-mTOR inhibition
@en
P2093
Hannah E Walters
Sylwia Deneka-Hannemann
P2860
P304
P356
10.18632/AGING.100872
P50
P577
2016-02-01T00:00:00Z