Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma - Wikidata - awgldk - TriplyDB

Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma

Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma

http://www.wikidata.org/entity/Q38966773

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The role of Merkel cell polyomavirus and other human polyomaviruses in emerging hallmarks of cancer Adjuvant Radiation Therapy and Chemotherapy in Merkel Cell Carcinoma: Survival Analyses of 6908 Cases From the National Cancer Data Base.Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinoma Tumor-Infiltrating Merkel Cell Polyomavirus-Specific T Cells Are Diverse and Associated with Improved Patient Survival.Merkel Cell Carcinoma Therapeutic Update.Rationale for immune-based therapies in Merkel polyomavirus-positive and -negative Merkel cell carcinomas.Merkel cell polyomavirus infection and Merkel cell carcinoma.Cancer treatment and the KIR-HLA system: an overview.How does the Merkel polyomavirus lead to a lethal cancer? Many answers, many questions, and a new mouse model.Immunotherapy with imiquimod and interferon alfa for metastasized Merkel cell carcinoma.Merkel cell carcinoma in the age of immunotherapy: Facts and hopes.Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC.Viral Oncology: Molecular Biology and Pathogenesis.The anti-PD-1 era - an opportunity to enhance radiotherapy for patients with bladder cancer.Immune evasion mechanisms and immune checkpoint inhibition in advanced merkel cell carcinoma.Avelumab and other recent advances in Merkel cell carcinoma.Integrated Cellular and Plasma Proteomics of Contrasting B-cell Cancers Reveals Common, Unique and Systemic Signatures.Targeting Merkel cell carcinoma by engineered T cells specific to T-antigens of Merkel cell polyomavirus.Prognostic factors and immunobiologic insights into Merkel cell carcinoma.Immune Checkpoint Inhibition for Pancreatic Ductal Adenocarcinoma: Current Limitations and Future Options Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA

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P2860

Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma

http://www.wikidata.org/entity/Q38966773

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

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2014年论文

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name

Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma

@en

type

label

Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma

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prefLabel

Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma

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2326-6066.CIR-14-0005

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Cancer immunology research

P1476

Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma

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P2093

Andrew Tegeder

http://www.w3.org/2001/XMLSchema#string

Christoph Willmes

http://www.w3.org/2001/XMLSchema#string

David Schrama

http://www.w3.org/2001/XMLSchema#string

Hideki Nakajima

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James S Hardwick

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Jayasri G Iyer

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Jürgen C Becker

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Kotaro Nagase

http://www.w3.org/2001/XMLSchema#string

Margaret Madeleine

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Mary L Disis

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P2860

Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator

Clonal integration of a polyomavirus in human Merkel cell carcinoma

Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens.

Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: analysis of 5823 cases as the basis of the first consensus staging system.

Antibodies to merkel cell polyomavirus T antigen oncoproteins reflect tumor burden in merkel cell carcinoma patients.

Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival.

Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors.

Merkel cell polyomavirus-specific CD8⁺ and CD4⁺ T-cell responses identified in Merkel cell carcinomas and blood.

Strategy for eliciting antigen-specific CD8+ T cell-mediated immune response against a cryptic CTL epitope of merkel cell polyomavirus large T antigen.

Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

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1071-1079

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scholarly article

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10.1158/2326-6066.CIR-14-0005

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11

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2

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Kelly G Paulson

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2014-08-12T00:00:00Z

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25116754

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4221542

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