Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas - Wikidata - awgldk - TriplyDB

Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

http://www.wikidata.org/entity/Q38967517

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The splicing factor SRSF6 is amplified and is an oncoprotein in lung and colon cancers Regulation of the Ras-MAPK and PI3K-mTOR Signalling Pathways by Alternative Splicing in Cancer Ron receptor tyrosine kinase signaling as a therapeutic target Misregulation of pre-mRNA alternative splicing in cancer Defective control of pre-messenger RNA splicing in human disease The role of splicing factors in deregulation of alternative splicing during oncogenesis and tumor progression Nonsense-mediated decay as a terminating mechanism for antisense oligonucleotides.A cytoplasmic quaking I isoform regulates the hnRNP F/H-dependent alternative splicing pathway in myelinating glia.A heroin addiction severity-associated intronic single nucleotide polymorphism modulates alternative pre-mRNA splicing of the μ opioid receptor gene OPRM1 via hnRNPH interactions.Emerging functions of SRSF1, splicing factor and oncoprotein, in RNA metabolism and cancer.KLF6 loss of function in human prostate cancer progression is implicated in resistance to androgen deprivation.Variants affecting exon skipping contribute to complex traits.Identification of differential splicing genes in gliomas using exon expression profiling.Antisense Modulation of RNA Processing as a Therapeutic Approach in Cancer Therapy.Intron retention in the alternatively spliced region of RON results from weak 3' splice site recognition.Evolutionarily emerged G tracts between the polypyrimidine tract and 3' AG are splicing silencers enriched in genes involved in cancer.The RNA-binding protein QKI suppresses cancer-associated aberrant splicing.Identification of cis-acting elements and splicing factors involved in the regulation of BIM Pre-mRNA splicing Transcriptome-wide identification and study of cancer-specific splicing events across multiple tumors.SRSF2 promotes splicing and transcription of exon 11 included isoform in Ron proto-oncogene.Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions Transcriptome-wide analysis of alternative RNA splicing events in Epstein-Barr virus-associated gastric carcinomas Post-transcriptional regulation in cancer progression : Microenvironmental control of alternative splicing and translation.Use of biotinylated plasmid DNA as a surrogate for HSV DNA to identify proteins that repress or activate viral gene expression.RBFOX2 is an important regulator of mesenchymal tissue-specific splicing in both normal and cancer tissues.Targeting RNA splicing for disease therapy.SRSF3 and hnRNP H1 regulate a splicing hotspot of HER2 in breast cancer cells.High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma.The prognostic potential of alternative transcript isoforms across human tumors.Protein and gene expression characteristics of heterogeneous nuclear ribonucleoprotein H1 in esophageal squamous cell carcinoma.Oncogenic alternative splicing switches: role in cancer progression and prospects for therapy.RNA splicing factors as oncoproteins and tumour suppressors.Making alternative splicing decisions during epithelial-to-mesenchymal transition (EMT).Splicing in oncogenesis and tumor suppression.Pre-mRNA splicing in disease and therapeutics.Aberrant splicing in neurological diseases.Alternative splicing in cancer: implications for biology and therapy.Alternative splicing of DNA damage response genes and gastrointestinal cancers.Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development

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Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

http://www.wikidata.org/entity/Q38967517

description

2011 nî lūn-bûn

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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2011年學術文章

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2011年學術文章

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name

Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

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type

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Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

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Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

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The EMBO Journal

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Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

@en

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Clare V Lefave

http://www.w3.org/2001/XMLSchema#string

Eric C Holland

http://www.w3.org/2001/XMLSchema#string

Gina L Rocco

http://www.w3.org/2001/XMLSchema#string

Luca Cartegni

http://www.w3.org/2001/XMLSchema#string

Sandra Vorlova

http://www.w3.org/2001/XMLSchema#string

Ying-Xian Pan

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The Hallmarks of Cancer

Contrasting effects of IG20 and its splice isoforms, MADD and DENN-SV, on tumor necrosis factor alpha-induced apoptosis and activation of caspase-8 and -3

Antisense abrogation of DENN expression induces apoptosis of leukemia cells in vitro, causes tumor regression in vivo and alters the transcription of genes involved in apoptosis and the cell cycle

A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion

Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme

Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Intronic binding sites for hnRNP A/B and hnRNP F/H proteins stimulate pre-mRNA splicing

Rapid and simple comparison of messenger RNA levels using real-time PCR.

WebLogo: A Sequence Logo Generator

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4084-4097

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scholarly article

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10.1038/EMBOJ.2011.259

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19

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30

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Cameron Brennan

Massimo Squatrito

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2011-09-13T00:00:00Z

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51634994

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21915099

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3209773

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