Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells.
about
A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations.The Establishment of a Hyperactive Structure Allows the Tumour Suppressor Protein p53 to Function through P-TEFb during Limited CDK9 Kinase Inhibition.THZ1 Reveals Roles for Cdk7 in Co-transcriptional Capping and PausingCdk7 mediates RPB1-driven mRNA synthesis in Toxoplasma gondii.THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitorsInhibitors of cyclin-dependent kinases as cancer therapeutics.Natural Compounds as Modulators of Cell Cycle Arrest: Application for Anticancer Chemotherapies.Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma.Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications.c-Myc deregulation induces mRNA capping enzyme dependency.MicroRNA profile in HBV-induced infection and hepatocellular carcinoma.Suppression of Adaptive Responses to Targeted Cancer Therapy by Transcriptional Repression.CDK regulation of transcription by RNAP II: Not over 'til it's over?The essential and multi-functional TFIIH complex.
P2860
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P2860
Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Cyclin-dependent kinase 7 cont ...... , and survival of tumor cells.
@en
type
label
Cyclin-dependent kinase 7 cont ...... , and survival of tumor cells.
@en
prefLabel
Cyclin-dependent kinase 7 cont ...... , and survival of tumor cells.
@en
P2093
P2860
P356
P1476
Cyclin-dependent kinase 7 cont ...... n, and survival of tumor cells
@en
P2093
Bert Klebl
Claudia Antrecht
Jan Eickhoff
Karen Baumgart
Michael Meisterernst
Sarah Lemcke
Thomas Albert
P2860
P304
P356
10.1128/MCB.00595-14
P407
P577
2014-07-21T00:00:00Z