Unraveling the Activation Mechanism of Taspase1 which Controls the Oncogenic AF4-MLL Fusion Protein

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Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer Pathways Taspase1: a 'misunderstood' protease with translational cancer relevance.

P2860

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P2860

Unraveling the Activation Mechanism of Taspase1 which Controls the Oncogenic AF4-MLL Fusion Protein

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http://www.wikidata.org/entity/Q38988891

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2015年学术文章

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Unraveling the Activation Mech ...... cogenic AF4-MLL Fusion Protein

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type

Item

label

Unraveling the Activation Mech ...... cogenic AF4-MLL Fusion Protein

@en

prefLabel

Unraveling the Activation Mech ...... cogenic AF4-MLL Fusion Protein

@en

P1476

Unraveling the Activation Mech ...... cogenic AF4-MLL Fusion Protein

@en

P2093

Christian Engelbrecht

http://www.w3.org/2001/XMLSchema#string

Eric Kowarz

http://www.w3.org/2001/XMLSchema#string

Samaneh Sabiani

http://www.w3.org/2001/XMLSchema#string

Tim Geppert

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P2860

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

Global and Hox-specific roles for the MLL1 methyltransferase

Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

Uncleaved TFIIA is a substrate for taspase 1 and active in transcription

A dual role for an aspartic acid in glycosylasparaginase autoproteolysis

Crystallographic snapshot of glycosylasparaginase precursor poised for autoprocessing

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

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386-395

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P31

scholarly article

P356

10.1016/J.EBIOM.2015.04.009

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Rolf Marschalek

Gisbert Schneider

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2015-04-16T00:00:00Z

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P5875

275773313

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26137584

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P932

4486195

http://www.w3.org/2001/XMLSchema#string

Unraveling the Activation Mechanism of Taspase1 which Controls the Oncogenic AF4-MLL Fusion Protein

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P2860

P2860

Unraveling the Activation Mechanism of Taspase1 which Controls the Oncogenic AF4-MLL Fusion Protein

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type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932