Ablation of a small transmembrane protein of Trypanosoma brucei (TbVTC1) involved in the synthesis of polyphosphate alters acidocalcisome biogenesis and function, and leads to a cytokinesis defect.
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Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammationCatalytic core of a membrane-associated eukaryotic polyphosphate polymeraseAcidocalcisomesNew insights into roles of acidocalcisomes and contractile vacuole complex in osmoregulation in protistsPolyphosphate and its diverse functions in host cells and pathogensThe role of acidocalcisomes in parasitic protists.Evolution of acidocalcisomes and their role in polyphosphate storage and osmoregulation in eukaryotic microbesExpansion of the target of rapamycin (TOR) kinase family and function in Leishmania shows that TOR3 is required for acidocalcisome biogenesis and animal infectivity.Target of rapamycin (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in Trypanosoma brucei.A novel protein kinase localized to lipid droplets is required for droplet biogenesis in trypanosomes.TgVTC2 is involved in polyphosphate accumulation in Toxoplasma gondii.Proteomic analysis of the acidocalcisome, an organelle conserved from bacteria to human cells.Adaptor protein-3 (AP-3) complex mediates the biogenesis of acidocalcisomes and is essential for growth and virulence of Trypanosoma brucei.Hyperosmotic stress induces aquaporin-dependent cell shrinkage, polyphosphate synthesis, amino acid accumulation, and global gene expression changes in Trypanosoma cruzi.Proteomic analysis of acidocalcisomes of Trypanosoma brucei uncovers their role in phosphate metabolism, cation homeostasis, and calcium signalingThe role of acidocalcisomes in the stress response of Trypanosoma cruzi.Volutin granules of Eimeria parasites are acidic compartments and have physiological and structural characteristics similar to acidocalcisomesTcPho91 is a contractile vacuole phosphate sodium symporter that regulates phosphate and polyphosphate metabolism in Trypanosoma cruziPhospholipid and glycolipid composition of acidocalcisomes of Trypanosoma cruzi.Requirement for acetyl-CoA carboxylase in Trypanosoma brucei is dependent upon the growth environment.Overexpression of a cytosolic pyrophosphatase (TgPPase) reveals a regulatory role of PP(i) in glycolysis for Toxoplasma gondii.Polyphosphate and acidocalcisomes.The acidocalcisome as a target for chemotherapeutic agents in protozoan parasites.Proteomics in Trypanosoma cruzi--localization of novel proteins to various organelles.Evidence for the role of vacuolar soluble pyrophosphatase and inorganic polyphosphate in Trypanosoma cruzi persistence.Trypanosoma brucei vacuolar transporter chaperone 4 (TbVtc4) is an acidocalcisome polyphosphate kinase required for in vivo infection.Essential regulation of cell bioenergetics in Trypanosoma brucei by the mitochondrial calcium uniporter.The acidocalcisome vacuolar transporter chaperone 4 catalyzes the synthesis of polyphosphate in insect-stages of Trypanosoma brucei and T. cruzi.The origin and evolution of the acidocalcisome and its interactions with other organelles.Calcium- and polyphosphate-containing acidocalcisomes in chicken egg yolk.Inorganic Polyphosphate Functions and Metabolism in Insects
P2860
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P2860
Ablation of a small transmembrane protein of Trypanosoma brucei (TbVTC1) involved in the synthesis of polyphosphate alters acidocalcisome biogenesis and function, and leads to a cytokinesis defect.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Ablation of a small transmembr ...... leads to a cytokinesis defect.
@en
type
label
Ablation of a small transmembr ...... leads to a cytokinesis defect.
@en
prefLabel
Ablation of a small transmembr ...... leads to a cytokinesis defect.
@en
P2093
P2860
P921
P356
P1433
P1476
Ablation of a small transmembr ...... leads to a cytokinesis defect.
@en
P2093
Jianmin Fang
Kildare Miranda
Peter Rohloff
Roberto Docampo
P2860
P304
P356
10.1042/BJ20070612
P407
P577
2007-10-01T00:00:00Z