Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy. - Wikidata - awgldk - TriplyDB

Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.

Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.

http://www.wikidata.org/entity/Q38998886

about

TDP-43 suppresses tau expression via promoting its mRNA instability.Advances in progressive supranuclear palsy: new diagnostic criteria, biomarkers, and therapeutic approaches.A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies.Propagation of Tau aggregates.Antisense Oligonucleotides: Translation from Mouse Models to Human Neurodegenerative Diseases.Expression of Tau Pathology-Related Proteins in Different Brain Regions: A Molecular Basis of Tau Pathogenesis.Gene suppression approaches to neurodegeneration.α-Lipoic acid improves abnormal behavior by mitigation of oxidative stress, inflammation, ferroptosis, and tauopathy in P301S Tau transgenic mice.Amyloid-β and tau complexity - towards improved biomarkers and targeted therapies.Antisense oligonucleotides: the next frontier for treatment of neurological disorders.Noncoding RNAs in neurodegeneration.Oligonucleotide therapies for disorders of the nervous system.Enzymatic Synthesis of 7',5'-Bicyclo-DNA Oligonucleotides.A role for tau in learning, memory and synaptic plasticity.Challenges for Alzheimer's Disease Therapy: Insights from Novel Mechanisms Beyond Memory Defects.Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay.Oligonucleotide therapeutics in neurodegenerative diseases.Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain.Sequestration of synaptic proteins by alpha-synuclein aggregates leading to neurotoxicity is inhibited by small peptide.Novel Key Players in the Development of Tau Neuropathology: Focus on the 5-Lipoxygenase.Antisense oligonucleotides in neurological disorders.2017 Year in Review and Message from the Editors to Our Reviewers.A silver lining for 24-hydroxycholesterol in Alzheimer's disease: The involvement of the neuroprotective enzyme sirtuin 1.Tau Kinetics in Neurons and the Human Central Nervous System The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease

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P2860

Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.

http://www.wikidata.org/entity/Q38998886

description

2017 nî lūn-bûn

@nan

2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

@zh-tw

2017年论文

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2017年论文

@zh

2017年论文

@zh-cn

name

Tau reduction prevents neurona ...... eeding in mice with tauopathy.

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type

label

Tau reduction prevents neurona ...... eeding in mice with tauopathy.

@en

prefLabel

Tau reduction prevents neurona ...... eeding in mice with tauopathy.

@en

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SCITRANSLMED.AAG0481

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Science Translational Medicine

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Tau reduction prevents neurona ...... seeding in mice with tauopathy

@en

P2093

Amy J Wegener

http://www.w3.org/2001/XMLSchema#string

Brandon Nichols

http://www.w3.org/2001/XMLSchema#string

C Frank Bennett

http://www.w3.org/2001/XMLSchema#string

Carey S Kebodeaux

http://www.w3.org/2001/XMLSchema#string

Eric E Swayze

http://www.w3.org/2001/XMLSchema#string

Guo Chen

http://www.w3.org/2001/XMLSchema#string

Hien Tran

http://www.w3.org/2001/XMLSchema#string

Holly B Kordasiewicz

http://www.w3.org/2001/XMLSchema#string

Kathleen M Schoch

http://www.w3.org/2001/XMLSchema#string

Marc I Diamond

http://www.w3.org/2001/XMLSchema#string

P2860

RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

Mechanisms of protein seeding in neurodegenerative diseases

Antisense oligonucleotides: treating neurodegeneration at the level of RNA

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy

Does neuroinflammation fan the flame in neurodegenerative diseases?

Neuropathological stageing of Alzheimer-related changes

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

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scholarly article

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10.1126/SCITRANSLMED.AAG0481

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374

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9

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Brandon B Holmes

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2017-01-01T00:00:00Z

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28123067

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5792300

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