Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies.

Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies.

Item
http://www.wikidata.org/entity/Q39016415
Secondary mutations as mediators of resistance to targeted therapy in leukemiaThe Biology and Targeting of FLT3 in Pediatric Leukemia.Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia.The Dual MEK/FLT3 Inhibitor E6201 Exerts Cytotoxic Activity against Acute Myeloid Leukemia Cells Harboring Resistance-Conferring FLT3 Mutations.Mechanisms of tumor cell resistance to the current targeted-therapy agents.Mechanisms of Resistance to FLT3 Inhibitors and the Role of the Bone Marrow Microenvironment.Tumor Trp53 status and genotype affect the bone marrow microenvironment in acute myeloid leukemia.Genomic instability is a principle pathologic feature of FLT3 ITD kinase activity in acute myeloid leukemia leading to clonal evolution and disease progression.Targeted therapies in Acute Myeloid Leukemia: a focus on FLT-3 inhibitors and ABT199.Targeting FLT3 Mutations in Acute Myeloid Leukemia.The FLT3 and PDGFR inhibitor crenolanib is a substrate of the multidrug resistance protein ABCB1 but does not inhibit transport function at pharmacologically relevant concentrations.Disruption of Wnt/β-catenin exerts anti-leukemia activity and synergizes with FLT3 inhibition in FLT3-mutant acute myeloid leukemia.Combinatorial targeting of XPO1 and FLT3 exerts synergistic anti-leukemia effects through induction of differentiation and apoptosis in FLT3-mutated acute myeloid leukemias: from concept to clinical trial.
P2860

Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies.

Item
http://www.wikidata.org/entity/Q39016415
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Reversal of acquired drug resi ...... t drug combination strategies.
@en
Reversal of acquired drug resi ...... t drug combination strategies.
@nl
type
label
Reversal of acquired drug resi ...... t drug combination strategies.
@en
Reversal of acquired drug resi ...... t drug combination strategies.
@nl
prefLabel
Reversal of acquired drug resi ...... t drug combination strategies.
@en
Reversal of acquired drug resi ...... t drug combination strategies.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Reversal of acquired drug resi ...... t drug combination strategies.
@en
P2093
P2860
P304
P31
P356
10.1158/1078-0432.CCR-13-2052
P407
P433
P478
P50
P577
P698
P921
P932