Discovery and identification of PIM-1 kinase inhibitors through a hybrid screening approach.

about

An overview of molecular hybrids in drug discovery.

P2860

Q38685830-6D58E8DF-0305-49A6-A946-CEFE89790481

P2860

Discovery and identification of PIM-1 kinase inhibitors through a hybrid screening approach.

Item

http://www.wikidata.org/entity/Q39024729

description

2014 nî lūn-bûn

@nan

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

2014年论文

@zh

2014年论文

@zh-cn

name

Discovery and identification o ...... h a hybrid screening approach.

@en

Discovery and identification o ...... h a hybrid screening approach.

@nl

type

Item

label

Discovery and identification o ...... h a hybrid screening approach.

@en

Discovery and identification o ...... h a hybrid screening approach.

@nl

prefLabel

Discovery and identification o ...... h a hybrid screening approach.

@en

Discovery and identification o ...... h a hybrid screening approach.

@nl

P1476

Discovery and identification o ...... h a hybrid screening approach.

@en

P2093

Guonian Zhu

http://www.w3.org/2001/XMLSchema#string

Kai Lei

http://www.w3.org/2001/XMLSchema#string

Kun Yu

http://www.w3.org/2001/XMLSchema#string

Lijuan Chen

http://www.w3.org/2001/XMLSchema#string

Mingfeng Shao

http://www.w3.org/2001/XMLSchema#string

Mingli Xiang

http://www.w3.org/2001/XMLSchema#string

Yiming Yuan

http://www.w3.org/2001/XMLSchema#string

P2860

Hallmarks of Cancer: The Next Generation

The protein kinase complement of the human genome

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers

Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase

Docking study yields four novel inhibitors of the protooncogene Pim-1 kinase

Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode

The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design

Rational evolution of a novel type of potent and selective proviral integration site in Moloney murine leukemia virus kinase 1 (PIM1) inhibitor from a screening-hit compound

Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases

P2888

s11030-014-9504-z

P304

335-344

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S11030-014-9504-Z

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2014-02-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

24519385

http://www.w3.org/2001/XMLSchema#string

Discovery and identification of PIM-1 kinase inhibitors through a hybrid screening approach.

about

P2860

P2860

Discovery and identification of PIM-1 kinase inhibitors through a hybrid screening approach.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P433

P478

P577

P698

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P433

P478

P577

P698